Emanuele Rubilotta, Francesco Ditonno, Marilena Gubbiotti, Alessandro Antonelli, Matteo Balzarro
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引用次数: 0
Abstract
Introduction: It is still uncertain whether detrusor underactivity (DUA) influences the outcomes of women undergoing surgery for stress urinary incontinence (SUI). Even less evidence is available about women with complicated stress urinary incontinence (C-SUI). The aim of the study was to assess outcomes of middle urethral sling (MUS) placement according to the type of SUI, and the impact of DUA on uncomplicated SUI (U-SUI) and C-SUI functional and surgical results.
Material and methods: The study was conducted among patients undergoing MUS. The population was divided into 4 groups: 1: C-SUI with DUA; 2: C-SUI without DUA; 3: U-SUI with DUA; and 4: U-SUI without DUA. Women were qualified for the DUA group if they met one of the Jeong, Abarbanel and Marcus, BVE, and PIP1 Griffiths criteria. Post-operative functional outcomes and differences in POUR rate, de novo overactive bladder syndrome (OAB), and SUI recurrence were examined.
Results: 142 women took part in the study, of whom 97 completed the 2-year follow-up. DUA was found in 54.6% (53/97) of patients. C-SUI was prevalent also in the no-DUA group (59.1%). Post-operative ICIQ-FLUTS improved more in the no-DUA patients compared to the DUA women. Post-operative Qmax was statistically significant higher the in no-DUA than in the DUA population. After surgery, neither the PVR nor the PVR ratio differed in the DUA and the no-DUA patients. C-SUI and U-SUI patients showed a POUR rate of 15.6%-12.1%, de novo OAB 12.5%-3%, tape incision 3.1%-3%, and SUI recurrence 4.6%-3%, respectively.
Conclusions: The impact of pre-operative DUA on the outcomes of patients undergoing MUS was negligible, even in C-SUI cases. DUA women with SUI, even if complicated, should not be excluded from this kind of surgery.
导言:对于接受压力性尿失禁(SUI)手术的女性而言,目前尚不确定逼尿肌活动不足(DUA)是否会影响手术效果。关于复杂性压力性尿失禁(C-SUI)的证据则更少。该研究旨在根据 SUI 的类型评估中段尿道吊带(MUS)置入术的效果,以及 DUA 对无并发症 SUI(U-SUI)和 C-SUI 功能和手术效果的影响:研究对象为接受 MUS 手术的患者。研究对象分为四组:1: 有 DUA 的 C-SUI;2: 无 DUA 的 C-SUI;3: 有 DUA 的 U-SUI;4: 无 DUA 的 U-SUI。符合 Jeong、Abarbanel 和 Marcus、BVE 和 PIP1 Griffiths 标准之一的妇女可被纳入 DUA 组。对术后功能结果以及POUR率、新发膀胱过度活动综合征(OAB)和SUI复发率的差异进行了研究:结果:142 名妇女参加了研究,其中 97 人完成了为期 2 年的随访。54.6%的患者(53/97)发现了膀胱过度活动症。在无 DUA 组中,C-SUI 也很普遍(59.1%)。与 DUA 女性患者相比,无 DUA 患者术后 ICIQ-FLUTS 改善程度更高。无 DUA 组术后 Qmax 在统计学上明显高于 DUA 组。术后,DUA 和无 DUA 患者的 PVR 和 PVR 比率均无差异。C-SUI和U-SUI患者的POUR率分别为15.6%-12.1%,新发OAB率为12.5%-3%,胶带切口率为3.1%-3%,SUI复发率为4.6%-3%:术前DUA对接受MUS手术的患者的预后影响微乎其微,即使在C-SUI病例中也是如此。有 SUI 的 DUA 妇女,即使病情复杂,也不应被排除在此类手术之外。