Paracetamol overdose in Danish children and adolescents during the Covid-19 restrictions.

IF 1 4区 医学 Q3 MEDICINE, GENERAL & INTERNAL Danish medical journal Pub Date : 2024-04-16 DOI:10.61409/A08230494
Oliver Nørholm Kempf, Thora Wesenberg Helt, Klaus Birkelund Johansen, Charlotte Rittig, Louise Lundby-Christensen, Marianne Sjølin Frederiksen, Pernille Mathiesen, Malene Boas, Preben Berg Nielsen, Annie Ellermann, Klaus Børch, Jens Jakob Petersen, Thomas Houmann Petersen, Cæcilie Trier Sønderskov, Jesper Andersen, Rasmus Gaardskær Nielsen, Eva Mosfeldt Jeppesen, Vibeke Brix Christensen
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Abstract

Introduction: To assess the effect of long-term isolation on the mental state of Danish youth. This study aimed to investigate trends in paracetamol overdoses among people under 18 years of age in Denmark during Covid-19 restrictions as an indicator of mental health.

Methods: All patients under the age of 18 years presenting with paracetamol overdose at one of the 18 paediatric departments in Denmark from 2016 to 2021 were included. They were identified in all Danish hospital databases using specific diagnostic codes.

Results: From 2016 to 2021, a total of 3,217 people under 18 years of age were admitted for paracetamol overdose. Among these, 86% (n = 2,755) were girls and 14% (n = 462) were boys. During 2020, a slight (7%) decrease in admissions was observed among both boys and girls compared with the preceding four-year mean value. In 2021, the number of overdoses among girls exceeded by 35% the former all-time high from 2016. Furthermore, the number of overdoses among girls exceeded the pre-four-year period mean value by 43%. Among boys, an 8% increase was seen from the highest ever previous value recorded in 2019 and a 23% increase compared with the previous four-year mean value.

Conclusions: During the first year of restrictions, a slight decrease in paracetamol overdoses was observed, possibly associated with limited accessibility. The second year showed a considerable increase in paracetamol overdoses, which may imply an affected mental state among youth during the prolonged lockdown restrictions as seen in previous epidemics. Therefore, further studies are warranted to develop a pandemic preparedness plan to protect general mental health.

Funding: None.

Trial registration: Not relevant.

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Covid-19 限制期间丹麦儿童和青少年过量服用扑热息痛的情况。
简介评估长期隔离对丹麦青少年精神状态的影响。本研究旨在调查丹麦18岁以下人群在Covid-19限制期间扑热息痛过量用药的趋势,以此作为精神健康的指标:方法:纳入2016年至2021年期间在丹麦18个儿科部门中的一个部门就诊的所有扑热息痛过量的18岁以下患者。结果:从 2016 年到 2021 年,在丹麦 18 个儿科医院就诊的扑热息痛过量的 18 岁以下患者中,共有 1.5 万名精神疾病患者:从 2016 年到 2021 年,共有 3217 名 18 岁以下儿童因扑热息痛过量而入院。其中,86%(n = 2755)为女孩,14%(n = 462)为男孩。与前四年的平均值相比,2020 年期间男孩和女孩的入院人数都略有下降(7%)。2021 年,女生吸毒过量人数比 2016 年的历史最高值高出 35%。此外,女生的吸毒过量人数比四年前的平均值高出 43%。在男生中,与 2019 年记录的历史最高值相比增加了 8%,与前四年的平均值相比增加了 23%:在限制措施实施的第一年,扑热息痛过量使用的情况略有减少,这可能与获取途径有限有关。第二年,过量服用扑热息痛的人数大幅增加,这可能意味着在长期的封锁限制期间,青少年的精神状态受到了影响,这在以往的流行病中也曾出现过。因此,有必要开展进一步研究,以制定大流行准备计划,保护一般心理健康:无:试验注册:不相关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Danish medical journal
Danish medical journal MEDICINE, GENERAL & INTERNAL-
CiteScore
2.30
自引率
6.20%
发文量
78
审稿时长
3-8 weeks
期刊介绍: The Danish Medical Journal (DMJ) is a general medical journal. The journal publish original research in English – conducted in or in relation to the Danish health-care system. When writing for the Danish Medical Journal please remember target audience which is the general reader. This means that the research area should be relevant to many readers and the paper should be presented in a way that most readers will understand the content. DMJ will publish the following articles: • Original articles • Protocol articles from large randomized clinical trials • Systematic reviews and meta-analyses • PhD theses from Danish faculties of health sciences • DMSc theses from Danish faculties of health sciences.
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