Co-Occurrence of Apathy and Impulse Control Disorders in Parkinson Disease: Variation across Multiple Measures.

IF 2.1 4区心理学 Q2 PSYCHOLOGY Archives of Clinical Neuropsychology Pub Date : 2024-10-25 DOI:10.1093/arclin/acae036

Bonnie M Scott, Robert S Eisinger, Roshan Mara, Amtul-Noor Rana, Sable Thompson, Michael S Okun, Aysegul Gunduz, Dawn Bowers

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Abstract

Objective: To determine if the co-occurrence of apathy and impulse control disorders (ICDs) in Parkinson disease is dependent on instrument selection and assess the concurrent validity of three motivation measures by examining interrelationships between them.

Method: Ninety-seven cognitively normal individuals with idiopathic Parkinson disease (PD) completed the Questionnaire for Impulsive-Compulsive Disorders in Parkinson Disease-Rating Scale (QUIP-RS) and three apathy measures: the Apathy Scale, Lille Apathy Rating Scale, and Item 4 of the Movement Disorder Society-Unified Parkinson Disease Rating Scale.

Results: Fifty (51.5%) participants were classified as apathetic on at least one measure, and only four individuals (4.3%) obtained clinically elevated scores on all three measures. The co-occurrence of apathy and ICD varied across measures.

Conclusions: We observed a co-occurrence of apathy and ICDs in PD patients with each apathy instrument; however, limited concurrent validity exists across measures. This is important for future investigations into shared pathophysiology and the design of future clinical trials aimed at improving the early detection and treatment of these debilitating syndromes.

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帕金森病患者的冷漠和冲动控制障碍同时存在：多重测量的差异。

目的确定帕金森病患者的冷漠和冲动控制障碍（ICDs）是否与工具选择有关，并通过研究三种动机测量方法之间的相互关系来评估它们的并发有效性：97名认知能力正常的特发性帕金森病（PD）患者完成了帕金森病冲动-强迫障碍问卷-评分量表（QUIP-RS）和三种淡漠测量方法：淡漠量表、里尔淡漠评分量表和运动障碍协会-统一帕金森病评分量表第4项：50名参与者（51.5%）在至少一项测量中被归类为淡漠，只有4人（4.3%）在所有三项测量中都获得了临床升高的分数。在不同的测量中，冷漠和 ICD 的并发率各不相同：结论：我们观察到，在使用每种移情工具的帕金森病患者中，移情和ICD都会同时出现；但是，不同工具之间的并发有效性有限。这对今后研究共同的病理生理学和设计旨在改善这些衰弱综合征的早期检测和治疗的临床试验非常重要。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Archives of Clinical Neuropsychology 医学-心理学

CiteScore

4.60

自引率

7.70%

发文量

358

审稿时长

6-12 weeks

期刊介绍： The journal publishes original contributions dealing with psychological aspects of the etiology, diagnosis, and treatment of disorders arising out of dysfunction of the central nervous system. Archives of Clinical Neuropsychology will also consider manuscripts involving the established principles of the profession of neuropsychology: (a) delivery and evaluation of services, (b) ethical and legal issues, and (c) approaches to education and training. Preference will be given to empirical reports and key reviews. Brief research reports, case studies, and commentaries on published articles (not exceeding two printed pages) will also be considered. At the discretion of the editor, rebuttals to commentaries may be invited. Occasional papers of a theoretical nature will be considered.