Novel foam dressing with through holes and negative pressure wound therapy with instillation and dwell time: a retrospective cohort study.

IF 1.4 4区 医学 Q3 DERMATOLOGY Wounds : a compendium of clinical research and practice Pub Date : 2024-03-01
Carlotta Scarpa, Martina Grigatti, Sandro Rizzato, Alberto Crema, Vincenzo Vindigni, Franco Bassetto
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Abstract

Background: NPWTi-d of a topical wound solution has been shown to benefit healing in a variety of wound types. This therapy has traditionally been applied via a standard ROCF-V. In 2017, a new ROCF-CC was introduced at the practice of the authors of the current manuscript for adjunctive management of patients with wounds with thick exudate and/or nonviable tissue and in cases in which surgical debridement is not available or not appropriate.

Objective: To compare the efficacy of NPWTi-d with ROCF-CC dressing (treatment) vs NPWTi-d with ROCF-V dressing (control).

Materials and methods: An observational retrospective cohort study of hospital records of patients with VLUs treated with NPWTi-d who received ROCF-CC dressings (n = 11) vs standard ROCF-V dressings (n = 11) was conducted. NPWTi-d was chosen to promote wound healing in VLUs that were not fully responsive to advanced dressings and/or compression bandage. Solution dwell time was 10 minutes, followed by 2.5-hour NPWT cycles at -125 mm Hg. Dressings were changed every 72 hours.

Results: Overall, mean ± SD duration of therapy and hospital length of stay were shorter in the treatment group vs the control group (duration of therapy, 8.63 days ± 7.05 vs 11.72 days ± 17.41, respectively; P = .05, and length of stay, 9.9 days ± 2.98 vs 12.81 days ± 4.26, respectively; P = .08), but these differences were not statistically significant. Mean wound area reduction was greater in the treatment group than in the control group (14.63 cm2 ± 13.24 and 10.72 cm2 ± 14.06, respectively; P = .51), but this was not significant.

Conclusion: ROCF-CC dressings were a useful tool in assisting wound bed preparation and reducing time to skin graft closure in this series of complex VLUs.

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带有通孔的新型泡沫敷料以及负压伤口疗法的灌注和停留时间:一项回顾性队列研究。
背景:事实证明,局部伤口溶液的 NPWTi-d 有助于各种类型伤口的愈合。这种疗法传统上是通过标准的 ROCF-V 来应用的。2017 年,本手稿作者的诊所引进了一种新型 ROCF-CC,用于辅助治疗伤口渗液较多和/或组织无活力的患者,以及无法或不适合手术清创的病例:比较NPWTi-d与ROCF-CC敷料(治疗)和NPWTi-d与ROCF-V敷料(对照)的疗效:对接受ROCF-CC敷料(11例)与标准ROCF-V敷料(11例)治疗的VLU患者的医院记录进行了观察性回顾性队列研究。选择 NPWTi-d 是为了促进对先进敷料和/或加压绷带反应不完全的 VLU 的伤口愈合。溶液停留时间为 10 分钟,然后在-125 毫米汞柱下进行 2.5 小时的 NPWT 循环。敷料每 72 小时更换一次:总体而言,治疗组与对照组相比,平均(±SD)治疗时间和住院时间更短(治疗时间分别为 8.63 天 ± 7.05 对 11.72 天 ± 17.41;P = .05;住院时间分别为 9.9 天 ± 2.98 对 12.81 天 ± 4.26;P = .08),但这些差异在统计学上并不显著。治疗组的平均伤口面积缩小幅度大于对照组(分别为 14.63 平方厘米 ± 13.24 和 10.72 平方厘米 ± 14.06;P = .51),但差异无统计学意义:结论:在这一系列复杂的 VLU 中,ROCF-CC 敷料是协助伤口床准备和缩短植皮闭合时间的有效工具。
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来源期刊
CiteScore
1.50
自引率
11.80%
发文量
77
审稿时长
6-12 weeks
期刊介绍: Wounds is the most widely read, peer-reviewed journal focusing on wound care and wound research. The information disseminated to our readers includes valuable research and commentaries on tissue repair and regeneration, biology and biochemistry of wound healing, and clinical management of various wound etiologies. Our multidisciplinary readership consists of dermatologists, general surgeons, plastic surgeons, vascular surgeons, internal medicine/family practitioners, podiatrists, gerontologists, researchers in industry or academia (PhDs), orthopedic surgeons, infectious disease physicians, nurse practitioners, and physician assistants. These practitioners must be well equipped to deal with a myriad of chronic wound conditions affecting their patients including vascular disease, diabetes, obesity, dermatological disorders, and more. Whether dealing with a traumatic wound, a surgical or non-skin wound, a burn injury, or a diabetic foot ulcer, wound care professionals turn to Wounds for the latest in research and practice in this ever-growing field of medicine.
期刊最新文献
Diving deep into healing: the promising role of fish skin in wound recovery. Effectiveness of negative pressure wound therapy in treating diabetic foot ulcers: a systematic review and meta-analysis of randomized controlled trials. Evaluating the number of cellular and/or tissue-based product applications required to treat diabetic foot ulcers and venous leg ulcers in non-hospital outpatient department settings. Skin cancer or locally advanced mammary carcinoma: a discussion of cutaneous pathology on the male chest. Use of silver collagen oxidized regenerated cellulose dressings in conjunction with negative pressure wound therapy: expert panel consensus recommendations.
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