[New frontiers in pacing: from myocardial pacing to conduction system pacing].

IF 0.7 Q4 CARDIAC & CARDIOVASCULAR SYSTEMS Giornale italiano di cardiologia Pub Date : 2024-05-01 DOI:10.1714/4252.42296
Raimondo Calvanese, Martina Nesti, Carlo Pignalberi, Pasquale Vergara, Lina Marcantoni, Federico Migliore, Giosuè Mascioli, Raimondo Pittorru, Manuel Antonio Conti, Alessandro Valleggi, Tania Sacco, Francesco Borrello, Amir Kol, Pietro Rossi, Gaetano Thiene, Francesco Zanon
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Abstract

For many years, cardiac pacing has been based on the stimulation of right ventricular common myocardium to correct diseases of the conduction system. The birth and the development of cardiac resynchronization have led to growing interest in the correction and prevention of pacing-induced dyssynchrony. Many observational studies and some randomized clinical trials have shown that conduction system pacing (CSP) can not only prevent pacing-induced dyssynchrony but can also correct proximal conduction system blocks, with reduction of QRS duration and with equal or greater effectiveness than biventricular pacing. Based on these results, many Italian electrophysiologists have changed the stimulation target from the right ventricular common myocardium to CSP. The two techniques with greater clinical impact are the His bundle stimulation and the left bundle branch pacing. The latter, in particular, because of its easier implantation technique and better electric parameters, is spreading like wildfire and is representing a real revolution in the cardiac pacing field. However, despite the growing amount of data, until now, the European Society of Cardiology guidelines give a very limited role to CSP.

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[起搏新领域:从心肌起搏到传导系统起搏]。
多年来,心脏起搏一直是通过刺激右心室心肌来纠正传导系统疾病。心脏再同步技术的诞生和发展使人们对纠正和预防起搏引起的不同步越来越感兴趣。许多观察性研究和一些随机临床试验表明,传导系统起搏(CSP)不仅可以预防起搏引起的不同步,还可以纠正近端传导系统阻滞,缩短 QRS 时程,其效果与双心室起搏相同或更佳。基于这些结果,许多意大利电生理学家已将刺激目标从右室共心肌改为 CSP。对临床影响较大的两种技术是 His 束刺激和左束支起搏。尤其是左束支起搏,由于其更简便的植入技术和更好的电参数,正在像野火一样蔓延,代表着心脏起搏领域的一场真正革命。然而,尽管数据越来越多,但直到现在,欧洲心脏病学会的指南对 CSP 的作用仍然非常有限。
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Giornale italiano di cardiologia
Giornale italiano di cardiologia CARDIAC & CARDIOVASCULAR SYSTEMS-
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