Gastrointestinal radionuclide imaging in pediatric age group.

Maria C Garganese, Milena Pizzoferro
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Abstract

Pediatric gastrointestinal imaging plays a crucial role in evaluating and managing digestive system disorders in children. This comprehensive review dives into the nuances of pediatric gastrointestinal imaging techniques, focusing on three specific modalities: gastric emptying scintigraphy (GES), intestinal transit scintigraphy (ITS), and gastrointestinal bleeding scintigraphy. GES involves real-time monitoring of stomach emptying using radiotracers and gamma camera technology. While challenges exist in standardizing protocols due to age-specific meal compositions, GES remains pivotal in diagnosing motility disorders, gastroesophageal reflux, and abdominal pain in children. ITS, utilizing [67Ga], provides insights into gastrointestinal motility disorders such as Hirschsprung disease. It aids in whole-gut transit evaluation, guiding surgical interventions and improving long-term clinical outcomes. Gastrointestinal bleeding scintigraphy, employing [99mTc], assists in diagnosing conditions like Meckel's diverticulum and occult bleeding, offering continuous monitoring to pinpoint the bleeding site along the entire gastrointestinal tract. SPECT-CT improves the accuracy and the standards of care. Each technique's protocol details, clinical indications, and diagnostic capabilities are thoroughly discussed, highlighting the importance of these non-invasive, functional imaging modalities in pediatric gastroenterology.

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小儿胃肠道放射性核素成像。
小儿胃肠造影在评估和治疗儿童消化系统疾病方面发挥着至关重要的作用。本综述深入探讨了小儿胃肠道成像技术的细微差别,重点介绍了三种特定模式:胃排空闪烁成像(GES)、肠道转运闪烁成像(ITS)和胃肠道出血闪烁成像。胃排空闪烁扫描是利用放射性核素和伽马相机技术对胃排空进行实时监测。虽然由于不同年龄段的膳食成分不同,在标准化方案方面存在挑战,但 GES 仍是诊断儿童运动障碍、胃食管反流和腹痛的关键。利用[67Ga]的 ITS 可以深入了解胃肠道运动障碍,如赫氏病。它有助于全肠道转运评估,指导手术干预,改善长期临床疗效。采用[99mTc]的胃肠道出血闪烁扫描有助于诊断梅克尔氏憩室和隐性出血等疾病,提供连续监测以精确定位整个胃肠道的出血部位。SPECT-CT 提高了治疗的准确性和标准。每种技术的方案细节、临床适应症和诊断能力都有详尽的讨论,突出了这些非侵入性功能成像模式在儿科胃肠病学中的重要性。
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来源期刊
the Quarterly Journal of Nuclear Medicine and Molecular Imaging
the Quarterly Journal of Nuclear Medicine and Molecular Imaging Medicine-Radiology, Nuclear Medicine and Imaging
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84
期刊介绍: The Quarterly Journal of Nuclear Medicine and Molecular Imaging publishes scientific papers on clinical and experimental topics of nuclear medicine. Manuscripts may be submitted in the form of editorials, original articles, review articles and special articles. The journal aims to provide its readers with papers of the highest quality and impact through a process of careful peer review and editorial work.
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