[A Case of Distal Gastrectomy and Left Segmentectomy for Hepatic Invasion of Gastric Cancer].

Q4 Medicine Japanese Journal of Cancer and Chemotherapy Pub Date : 2024-04-01
Yuta Nakayama, Kazuki Koyama, Koichiro Shimizu, Rei Kanemoto, Nozomi Urata, Keisuke Komori, Mamoru Uchiyama, Yoshihiro Suzuki, Yasushi Rino, Aya Saito
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Abstract

A 66-year-old male came to our hospital because of occult blood in stool and anemia. The patient was diagnosed as unresectable advanced gastric cancer,( ML/Less, type 2, tub2, cT4b[liver], cN+, cM0, cStage Ⅳ, HER2 negative). He was given oxaliplatin plus S-1 therapy. In the 3rd course of chemotherapy, he had severe anemia, and active bleeding from the tumor. To control the bleeding he underwent distal gastrectomy, lateral segmentectomy of the liver, and S4 partial hepatectomy. The patient underwent adjuvant chemotherapy with docetaxel plus S-1. Three months after surgery, lymph nodes recurrence was observed. He underwent second-line therapy with paclitaxel and ramucirumab. Seven months after surgery, lymph nodes recurrence was increased. He was switched to third-line therapy with nivolumab. He is currently arrive 12 months after surgery.

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[胃癌肝脏受侵的远端胃切除术和左段切除术一例]。
一名 66 岁的男性因大便隐血和贫血来我院就诊。患者被诊断为不可切除的晚期胃癌(ML/Less,2 型,tub2,cT4b[肝],cN+,cM0,c Ⅳ期,HER2 阴性)。他接受了奥沙利铂加 S-1 治疗。在第 3 个化疗疗程中,他出现了严重贫血和肿瘤出血。为了控制出血,他接受了远端胃切除术、肝脏侧段切除术和 S4 部分肝切除术。患者接受了多西他赛+S-1的辅助化疗。术后三个月,发现淋巴结复发。他接受了紫杉醇和雷莫芦单抗的二线治疗。术后七个月,淋巴结复发。他转而接受了 nivolumab 的三线治疗。目前他已术后 12 个月。
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CiteScore
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