[A case of neurosarcoidosis initially diagnosed as cervical spondylotic myelopathy, leading to diagnosis by gadolinium contrast-enhanced MRI].

Q4 Medicine Clinical Neurology Pub Date : 2024-05-24 Epub Date: 2024-04-25 DOI:10.5692/clinicalneurol.cn-001921
Ayano Matsuyoshi, Daiji Uchiyama, Toshinori Kawanami, Yukiko Inamori, Wataru Shiraishi
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Abstract

A 70-year-old female presented with bilateral numbness in her upper limbs. She was diagnosed with cervical spondylotic myelopathy and underwent cervical laminoplasty. However, there was no significant improvement in sensory disturbance, and at 6 months after surgery, she developed subacute motor and gait disturbance in four extremities. Spinal MRI revealed a long lesion of the spinal cord with edema, and a part of the lesion showed gadolinium contrast enhancement. Bronchoscopy revealed an elevated CD4/8 ratio, and gallium scintigraphy demonstrated an accumulation in the hilar lymph nodes, leading to a diagnosis of neurosarcoidosis. In case of rapid deterioration during the course of cervical spondylotic myelopathy, neurosarcoidosis should be considered as a differential diagnosis, which can be assessed by contrast-enhanced MRI.

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[一例神经肉芽肿病最初被诊断为颈椎病,后经钆对比剂增强磁共振成像确诊]。
一名 70 岁的女性因双侧上肢麻木前来就诊。她被诊断为颈椎病,并接受了颈椎椎板成形术。然而,感觉障碍没有明显改善,术后 6 个月,她的四肢出现了亚急性运动和步态障碍。脊髓核磁共振成像显示脊髓有一长条状病变,伴有水肿,部分病变呈钆对比增强。支气管镜检查显示 CD4/8 比率升高,镓闪烁扫描显示肺门淋巴结有积聚,诊断为神经肉芽肿病。如果颈椎病在病程中迅速恶化,神经肉芽肿病应被视为鉴别诊断,可通过对比增强磁共振成像进行评估。
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来源期刊
Clinical Neurology
Clinical Neurology Medicine-Neurology (clinical)
CiteScore
0.30
自引率
0.00%
发文量
147
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