[Loxoscelism with acute compartment síndrome: A case report with successful conclusion].

Itzel Yoselin Sánchez-Perez, Yareni Chávez-Ríos, Sergio Gerardo Moreno-Hernández, Andrea Velasco-Medina, Guillermo Velázquez-Sámano, Espiridión Ramos-Martínez
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Abstract

Background: Loxoscelism is a toxic clinical condition caused by the bite of spiders of the genus Loxosceles, with wide distribution throughout the world.1 Phospholipase D is responsible for dermonecrosis, inflammation, platelet aggregation, hemolysis, alteration of vascular permeability, cytotoxicity, nephrotoxicity, acute renal failure, among other symptoms involved with this protein.

Case report: 27-year-old male patient, who began with a sudden episode of intense pain in the right hand, in the metacarpus and metacarpophalangeal joints. On clinical examination, the upper extremity was noted to have increased volume, extensive edema, hyperemia, and increased local temperature; The lesion progressed to extensive necrosis. Fasciotomies were performed, from distal to proximal, and release of the second and third finger compartment through longitudinal radial and ulnar incisions. A skin autograft was placed, obtained from the anterior surface of the right thigh. Opioid analgesics, non-steroidal anti-inflammatory drugs, corticosteroids, and antibiotics were administered. The skin biopsy reported: inflammatory infiltrate with neutrophils, ulceration, and bacterial colonies. After 27 days he had a favorable evolution, so he was discharged to his home, with follow-up by staff from the Outpatient Service.

Conclusion: Cutaneous loxoscelism, as a cause of acute compartment syndrome of the hand, is rare, but should be considered in an area endemic for Loxosceles spp. Surgical decompression of the affected compartments represents a decisive factor in the treatment of patients.

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[嗜铬细胞瘤伴急性隔室综合征:成功结案的病例报告]。
背景:1 磷脂酶 D 可导致皮肌坏死、炎症、血小板聚集、溶血、血管通透性改变、细胞毒性、肾毒性、急性肾衰竭等症状:27 岁男性患者,起初右手掌骨和掌指关节突然剧烈疼痛。临床检查发现,上肢体积增大、广泛水肿、充血和局部温度升高;病变发展为广泛坏死。医生从远端到近端进行了筋膜切开术,并通过桡侧和尺侧纵向切口松解了第二和第三指间室。从右侧大腿前侧取皮,进行了自体皮肤移植。治疗过程中使用了阿片类镇痛药、非甾体抗炎药、皮质类固醇激素和抗生素。皮肤活检报告显示:炎性浸润伴有中性粒细胞、溃疡和细菌菌落。27 天后,患者病情好转,出院回家,由门诊部工作人员进行随访:结论:作为手部急性隔室综合征病因的皮肤梭形虫病十分罕见,但在梭形虫病流行的地区应予以重视。
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