Association between hemoglobin levels and diabetic foot ulcer in patients with type 2 diabetes: a cross-sectional study.

IF 1.4 4区医学 Q3 DERMATOLOGY Wounds : a compendium of clinical research and practice Pub Date : 2024-03-01

Fengying Jiang, Qingyang Liu, Qiubo Wang

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Abstract

Background: Anemia is prevalent among patients with T2DM with DFU. However, there is limited research on the relationship between Hb level and DFU.

Objective: To investigate the characteristics and relationship between Hb level and prognosis in patients with DFU.

Materials and methods: A total of 212 patients with T2DM were included and grouped according to the presence (n = 105) or absence (n = 107) of DFU. The independent t test and multiple logistic regression analysis were used to analyze the effect of different factors on the occurrence of anemia in patients with DFU and whether Hb level could be used to predict prognosis.

Results: There were significant differences in clinical indicators that directly or indirectly contributed to anemia in patients with DFU (P < .05). Hb level was independently associated with DFU (OR, 0.899; P < .05). Hb levels were significantly decreased in patients aged 65 years or older (P < .05). Mild anemia was prevalent among most patients with DFU (59.62%). Hb level decreased with the severity of foot ulcer (P < .05) and was correlated with the duration of diabetes (R2 = 0.653; P < .05). The AUC value was 0.82, with a cutoff value of 122.5 g/L to identify patients with DFU at high risk of adverse outcomes.

Conclusion: Anemia is common in patients with DFU. Anemia is a marker of DFU severity, and Hb level can predict poor prognosis in patients with DFU.

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2 型糖尿病患者血红蛋白水平与糖尿病足溃疡之间的关系：一项横断面研究。

背景：T2DM 合并 DFU 患者中普遍存在贫血现象。然而，关于 Hb 水平与 DFU 关系的研究却很有限：材料与方法：共 212 例 T2DM 患者：共纳入 212 例 T2DM 患者，根据是否存在 DFU 分组（105 例）。采用独立t检验和多元Logistic回归分析，分析不同因素对DFU患者贫血发生的影响，以及Hb水平是否可用于预测预后：直接或间接导致DFU患者贫血的临床指标存在明显差异（P < .05）。血红蛋白水平与 DFU 无关（OR，0.899；P < .05）。65 岁或以上患者的血红蛋白水平明显下降（P < .05）。大多数 DFU 患者普遍存在轻度贫血（59.62%）。Hb 水平随足部溃疡的严重程度而降低（P < .05），并与糖尿病持续时间相关（R2 = 0.653; P < .05）。AUC值为0.82，以122.5 g/L为临界值，可确定DFU患者出现不良后果的高风险：结论：贫血在 DFU 患者中很常见。结论：贫血在 DFU 患者中很常见，贫血是 DFU 严重程度的标志，血红蛋白水平可预测 DFU 患者的不良预后。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Wounds : a compendium of clinical research and practice 医学-皮肤病学

CiteScore

1.50

自引率

11.80%

发文量

审稿时长

6-12 weeks

期刊介绍： Wounds is the most widely read, peer-reviewed journal focusing on wound care and wound research. The information disseminated to our readers includes valuable research and commentaries on tissue repair and regeneration, biology and biochemistry of wound healing, and clinical management of various wound etiologies. Our multidisciplinary readership consists of dermatologists, general surgeons, plastic surgeons, vascular surgeons, internal medicine/family practitioners, podiatrists, gerontologists, researchers in industry or academia (PhDs), orthopedic surgeons, infectious disease physicians, nurse practitioners, and physician assistants. These practitioners must be well equipped to deal with a myriad of chronic wound conditions affecting their patients including vascular disease, diabetes, obesity, dermatological disorders, and more. Whether dealing with a traumatic wound, a surgical or non-skin wound, a burn injury, or a diabetic foot ulcer, wound care professionals turn to Wounds for the latest in research and practice in this ever-growing field of medicine.