Case report of crusted scabies, brief review of its pathophysiology and latest data.

IF 0.7 Q3 MEDICINE, GENERAL & INTERNAL AME Case Reports Pub Date : 2024-02-21 eCollection Date: 2024-01-01 DOI:10.21037/acr-23-125
Dimitrios Alexandris, Nektarios Alevizopoulos, Panagiotis Nennes, Elina Basagianni, Poulcheria Rousou, Maria Kioupi, Foteini Gerakini
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Abstract

Background: Crusted scabies is a rare form of parasitic infection provoked by a massive infestation of the ectoparasite Sarcoptes scabiei varietas hominis on human skin. It is an extremely contagious type of disease and can even lead to a social stigma. In European countries like Greece, many cases remain undiagnosed for long periods, causing extreme distress in the patient's everyday life and social environment.

Case description: Herein, we present a case of an 86-year-old woman with crusted scabies in Greece, who remained undiagnosed for 5 months. Massive hyperkeratotic plaques on the extremities, and face, palmoplantar keratoderma, and numerous small erythematous papules on the torso with extreme itch were the main clinical manifestations of the patient. Dermoscopy revealed the parasite. All necessary decontamination measures were taken by personnel. Treatment was administered and a complete cure of the disease was observed.

Conclusions: In this case, the use of dermoscopy has attributed to precise crusted scabies diagnosis and acute pharmacological management of the patient. Early diagnosis of such diseases not only saves patients from lethal secondary infections, but also reduces the risk of a massive scabies outbreak. We also conducted a mini-review, analyzing all recent data concerning crusted scabies macroscopic, dermatoscopic, and histological images. All new information concerning the pathophysiological mechanism of crusted scabies manifestation, updated treatment options, and potential resistance to widely-used treatments are provided.

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结痂性疥疮病例报告、病理生理学简述和最新数据。
背景:结痂性疥疮是一种罕见的寄生虫感染,由疥螨变种大量寄生在人体皮肤上引起。它是一种传染性极强的疾病,甚至会导致社会耻辱。在希腊等欧洲国家,许多病例长期得不到诊断,给患者的日常生活和社会环境造成极大困扰:在此,我们介绍一例在希腊患有结痂性疥疮的 86 岁妇女的病例。患者的主要临床表现是四肢和面部出现大面积角化过度斑块、掌跖角化症,躯干上有许多小的红斑丘疹,伴有极度瘙痒。皮肤镜检查发现了寄生虫。医护人员采取了一切必要的净化措施。经过治疗,该病被完全治愈:在本病例中,使用皮肤镜对结痂性疥疮进行了精确诊断,并对患者进行了急性药物治疗。对此类疾病的早期诊断不仅能使患者免于致命的继发感染,还能降低疥疮大规模爆发的风险。我们还进行了一次小型回顾,分析了有关结痂疥疮宏观、皮肤镜和组织学图像的所有最新数据。我们还提供了有关疥疮结痂表现的病理生理机制、最新治疗方案以及对广泛使用的治疗方法的潜在耐药性的所有新信息。
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