2023, A Landmark Year in Biomedical Research; A Turning Point in Medical History.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-03-01 DOI:10.22074/cellj.2024.2024274.1523

Bahareh Sadri, Massoud Vosough

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Abstract

The rapid development of knowledge on healthy nutrition, and hygiene practices, as well as the advent of antibiotics and vaccines, has led to increased life expectancy in the recent century. The extended lifespan has brought new challenges for healthcare professionals, including the management of chronic degenerative diseases, malignancies, and autoimmune disorders. Advanced therapeutic medicinal products (ATMPs) have emerged as a promising frontier alongside conventional therapeutic modalities, offering innovative solutions through cell-based therapies, gene therapy, and tissue engineering. Recent years have witnessed remarkable advancements in regenerative medicine and the launching of innovative ATMPs. Numerous ATMPs have been registered and approved by regulatory agencies for the management of different diseases in 2023. The approval of groundbreaking therapies around the world has made 2023 an exceptional year. Novel ATMPs and the development of artificial intelligence (AI) in 2023 will pave the way for the integration of ATMPs and advanced technologies in personalized medicine, early diagnosis and targeted treatments.

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2023，生物医学研究中具有里程碑意义的一年；医学史上的转折点。

随着健康营养和卫生习惯知识的快速发展，以及抗生素和疫苗的出现，人们的预期寿命在近一个世纪里得到了延长。寿命的延长给医护人员带来了新的挑战，包括慢性退行性疾病、恶性肿瘤和自身免疫性疾病的治疗。先进治疗药物产品（ATMP）已成为与传统治疗方式并驾齐驱的前景广阔的前沿领域，通过细胞疗法、基因疗法和组织工程提供创新解决方案。近年来，再生医学取得了长足的进步，创新型 ATMP 也相继问世。2023 年，监管机构已注册并批准了大量用于治疗不同疾病的 ATMP。全球突破性疗法的批准使 2023 年成为不同寻常的一年。2023年，新型ATMP和人工智能（AI）的发展将为ATMP和先进技术在个性化医疗、早期诊断和靶向治疗方面的融合铺平道路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.

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