Auditory brainstem responses in young adults with Down syndrome.

J E Widen, R C Folsom, G Thompson, W R Wilson
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Abstract

Auditory brainstem response (ABR) wave V detection levels, latency, and amplitude were studied in a group of 15 young adults with Down syndrome for whom behavioral measures of hearing sensitivity were also obtained. Comparisons were made to a group of nonretarded control subjects matched by age and sex. Auditory brainstem response detection levels were elevated, response amplitude was reduced, and latency-intensity functions were significantly steeper for the subjects with Down syndrome than for the control group. These findings were associated with a high frequency (8000 Hz) hearing loss prevalent in the otherwise normal-hearing experimental group.

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唐氏综合症青年患者的听觉脑干反应。
在一组15名唐氏综合征年轻成人中,研究了听觉脑干反应(ABR)波V检测水平、潜伏期和振幅,并获得了听力敏感性的行为测量。与一组按年龄和性别匹配的非智障对照组进行比较。唐氏综合征患者的听觉脑干反应检测水平升高,反应幅度降低,潜伏期-强度函数明显比对照组陡峭。这些发现与在其他听力正常的实验组中普遍存在的高频(8000hz)听力损失有关。
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