{"title":"[A case of primary central nervous system lymphoma of the sellar region presented with panhypopituitarism].","authors":"Ayaka Seki, Fumiaki Henmi, Shinji Ito, Hironori Uruga, Kei Arisawa, Yoshikazu Uesaka","doi":"10.5692/clinicalneurol.cn-001941","DOIUrl":null,"url":null,"abstract":"<p><p>The patient is a 41-year-old woman. She presented with vomiting and lightheadedness, and blood tests showed a generalized decrease in pituitary hormones and hyperprolactinemia. A head MRI showed increased signal intensity lesions on FLAIR image in the pituitary stalk, corpus callosum, periventricular area of the fourth ventricle, and superior cerebellar peduncle. The lesions were homogeneously enhanced, and a brain biopsy confirmed the diagnosis of primary diffuse large B-cell lymphoma of the central nervous system, and chemotherapy was started. Although the suprasellar region is a rare site for primary central nervous system lymphoma (PCNSL), it should be diagnosed early by biopsy.</p>","PeriodicalId":39292,"journal":{"name":"Clinical Neurology","volume":" ","pages":"356-360"},"PeriodicalIF":0.0000,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Neurology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5692/clinicalneurol.cn-001941","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/4/25 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
Abstract
The patient is a 41-year-old woman. She presented with vomiting and lightheadedness, and blood tests showed a generalized decrease in pituitary hormones and hyperprolactinemia. A head MRI showed increased signal intensity lesions on FLAIR image in the pituitary stalk, corpus callosum, periventricular area of the fourth ventricle, and superior cerebellar peduncle. The lesions were homogeneously enhanced, and a brain biopsy confirmed the diagnosis of primary diffuse large B-cell lymphoma of the central nervous system, and chemotherapy was started. Although the suprasellar region is a rare site for primary central nervous system lymphoma (PCNSL), it should be diagnosed early by biopsy.
患者是一名 41 岁的女性。她出现呕吐和头晕,血液检查显示垂体激素普遍减少,并伴有高泌乳素血症。头部核磁共振成像显示,垂体柄、胼胝体、第四脑室室周区和小脑上梗的FLAIR图像上出现信号强度增高的病变。病变呈均匀强化,脑活检确诊为中枢神经系统原发性弥漫大 B 细胞淋巴瘤,并开始化疗。虽然小脑上部是原发性中枢神经系统淋巴瘤(PCNSL)的罕见部位,但应尽早通过活检确诊。