[Cerebrospinal fluid rhinorrhea secondary to ethmoidal carcinoma: case report].

Bryan Eduardo García-López, Diana Mondragón-García, Abigail Morán-Domínguez, Itzel Yoselin Sánchez-Pérez, Guillermo Velázquez-Sámano, Andrea Aida Velasco-Medina
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Abstract

Background: The first report of cerebrospinal fluid rhinorrhea (CSFR) was described in 1679. In 1826 it was reported that one of the possible causes of CSFR was a fistula between the subarachnoid space and the nasal cavity. In 1903, chemical analysis of the fluid was proposed as a diagnostic criterion. In Mexico there has been 32 case reports.

Case report: Forty-nine years old female with a history of nasal polyposis, profuse rhinorrhea and cephalea who attends the allergy department with the suspicion of allergic rhinitis. After anamnesis and physical evaluation, CSFR was suspected. Chemical analysis of the fluid, head CT and biopsy of nasal polyp were performed. An etmoidal fistula associated with carcinoma was confirmed.

Conclusions: Spontaneous fistulas are rare but can erosionate the bone and adjacent tissues. Diagnosis is based on the clinical findings, patient's history and complementary studies such as beta-2-transferrin determination in nasal fluid.

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[乙状体癌继发脑脊液鼻出血:病例报告]。
背景:脑脊液鼻出血(CSFR)的首次报道是在 1679 年。1826 年,有报道称 CSFR 的可能病因之一是蛛网膜下腔和鼻腔之间的瘘管。1903 年,有人提出将脑脊液的化学分析作为诊断标准。墨西哥有 32 例病例报告:病例报告:49 岁女性,有鼻息肉、大量鼻出血和头痛病史,因怀疑患有过敏性鼻炎而到过敏科就诊。经过询问病史和体格检查,怀疑是 CSFR。对液体进行了化学分析、头部 CT 和鼻息肉活检。结论是:自发性瘘管非常罕见,但对患者的影响却很大:自发性瘘管很少见,但会侵蚀骨骼和邻近组织。诊断依据是临床表现、患者病史和辅助检查,如鼻腔液中 beta-2 转铁蛋白的测定。
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