Influence of medications on fall risk assessment in maintenance hemodialysis patients: A cross-sectional study.

Q3 Medicine International Journal of Critical Illness and Injury Science Pub Date : 2024-01-01 Epub Date: 2024-03-27 DOI:10.4103/ijciis.ijciis_57_23

Raghad M Ismail, Dixon Thomas, Rajaram Jagdale

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Abstract

Background: Multiple factors influence the fall risk in end-stage kidney disease. This study aims to investigate how medication factors influence the interpretation of fall risk due to age, gender, and years of dialysis treatment among patients undergoing hemodialysis (HD).

Methods: A cross-sectional study was carried out in 2023 using the Johns Hopkins Fall Risk Assessment tool. Participants were recruited from the HD unit at a tertiary care academic medical center in Ajman, UAE. Data were analyzed between different ages, genders, and years on HD categories with or without medication factors.

Results: Data were collected and analyzed for 44 patients. The fall risk of the study population assessed with the Kruskal-Wallis test showed no difference between different age groups (P = 0.43) but did show a significant difference when the score of medication factor was removed from the fall risk estimation (P = 0.002). A pairwise analysis showed fall risk score of the age group 46-60 years was differing from the age cohort >60 (P < 0.001). A positive moderate correlation (Spearman's correlation coefficient 0.514 was found, with a P < 0.001) was seen with an increase in age and fall risk only when the medication factor was removed from the fall risk estimation. Results on gender or duration of dialysis were insignificant.

Conclusion: Medication factors being a significant contributor to fall risk among the study population was found to mask the fall risk difference between age groups 46-60 years and >60 years. Such influence was not found for gender or duration of dialysis.

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药物对维持性血液透析患者跌倒风险评估的影响：横断面研究

背景：多种因素影响终末期肾病患者的跌倒风险。本研究旨在调查药物因素如何影响血液透析（HD）患者因年龄、性别和透析治疗年限而导致的跌倒风险：这项横断面研究于 2023 年进行，使用的是约翰-霍普金斯跌倒风险评估工具。参与者来自阿联酋阿治曼一家三级医疗学术医疗中心的血液透析室。分析了不同年龄、性别、服用或不服用药物的血液透析患者的数据：收集并分析了 44 名患者的数据。用 Kruskal-Wallis 检验法对研究人群的跌倒风险进行了评估，结果显示不同年龄组之间没有差异（P = 0.43），但如果从跌倒风险评估中剔除药物因素得分，则显示出显著差异（P = 0.002）。配对分析表明，46-60 岁年龄组与大于 60 岁年龄组的跌倒风险得分存在差异（P < 0.001）。只有当从跌倒风险评估中剔除药物因素时，才会发现年龄的增加与跌倒风险呈中度正相关（斯皮尔曼相关系数为 0.514，P < 0.001）。结论：药物因素是导致跌倒风险的重要因素：结论：研究发现，药物因素是导致研究人群跌倒风险的重要因素，它掩盖了 46-60 岁年龄组和 60 岁以上年龄组之间的跌倒风险差异。性别和透析时间的影响则不明显。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Critical Illness and Injury Science Medicine-Emergency Medicine

CiteScore

1.40

自引率

0.00%

发文量

期刊介绍： IJCIIS encourages research, education and dissemination of knowledge in the field of Critical Illness and Injury Science across the world thus promoting translational research by striking a synergy between basic science, clinical medicine and public health. The Journal intends to bring together scientists and academicians in the emergency intensive care and promote translational synergy between Laboratory Science, Clinical Medicine and Public Health. The Journal invites Original Articles, Clinical Investigations, Epidemiological Analysis, Data Protocols, Case Reports, Clinical Photographs, review articles and special commentaries. Students, Residents, Academicians, Public Health experts and scientists are all encouraged to be a part of this initiative by contributing, reviewing and promoting scientific works and science.