The evolution of patient-reported outcome measures after a first lateral ankle sprain: A prospective study

IF 1.9 3区 医学 Q2 ORTHOPEDICS Foot and Ankle Surgery Pub Date : 2024-04-30 DOI:10.1016/j.fas.2024.04.012
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引用次数: 0

Abstract

Purpose

A lateral ankle sprain is the most common musculoskeletal injury in the physically active population. However, it is unclear how the clinical condition evolves during the period after the injury and what proportion of patients develops chronic symptoms. Therefore, the purpose of this study is to assess the evolution of patient-reported outcome measures after a first time lateral ankle sprain.

Methods

A prospective clinical study assessed the patient-reported outcome measures (PROMs) of a consecutive group of 100 patients during 1 year after a first lateral ankle sprain. The Karlsson score and Foot and Ankle Outcome Score (FAOS) were assessed at 6 weeks, 3 months, 6 months, 9 months and 1 year. The Cumberland Ankle Instability Tool (CAIT)-score was assessed at 6 months, 9 months and 1 year. The difference between the time points of all scores was analysed using the positive change over time (binomial test versus 50%) and the difference in score (signed rank test). The time to sustained excellent level was also assessed overall and in several subgroups: age, gender, degree of injury (2 or 3), avulsion fracture, use of crutches, use of cast. Differences between subgroups were assessed by a generalized log-rank test.

Results

All clinical scores demonstrated an improvement up to 12 months after the sprain. The median Karlsson score (interquartile range) improved from 62 (50−80) at 6 weeks to 90 (72−100) at 3 months, to 97 (82−100) at 6 months to 100 (90−100) at 9 months, to 100 (100−100) at 1 year. The analysis of positive change over time demonstrated a significant positive change (P-value <.0005) between all time points except between 6 weeks and 12 weeks when using the FAOS quality score. The difference in score demonstrated a significant change (P-value <.01) between all time points except between 36 weeks and 48 weeks when using the FAOS pain and FAOS sports score. Age and presence of an avulsion fracture were correlated with a slower recovery and worse results. At 1 year, in total 13 patients (13%) had a worse outcome corresponding to a Karlsson score < 81 or CAIT score < 24.

Conclusion

The clinical condition after a first ankle sprain demonstrated a significant improvement in PROMs between the different time points in the first year. Twelve months after a first lateral ankle sprain 13% had a fair or poor outcome. Higher age and presence of an avulsion fracture were correlated with a slower recovery and worse results. This information is useful in clinical practice to predict further progression and inform patients. Moreover, it is valuable to improve treatment strategies.

Level of evidence

Level II (prospective cohort study)

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首次外侧踝关节扭伤后患者报告结果的演变:前瞻性研究。
目的:外侧踝关节扭伤是体力活动人群中最常见的肌肉骨骼损伤。然而,目前还不清楚受伤后的临床症状是如何演变的,也不清楚有多大比例的患者会出现慢性症状。因此,本研究旨在评估首次外侧踝关节扭伤后患者报告的结果指标的演变情况:一项前瞻性临床研究评估了首次外侧踝关节扭伤后 1 年内连续 100 名患者的患者报告结果指标(PROMs)。分别在 6 周、3 个月、6 个月、9 个月和 1 年时评估卡尔森评分和足踝结果评分(FAOS)。坎伯兰踝关节不稳定性工具(CAIT)评分在 6 个月、9 个月和 1 年时进行评估。所有评分的时间点之间的差异均采用随时间的正向变化(二项式检验与 50%)和评分差异(符号秩检验)进行分析。此外,还对达到持续优秀水平的时间进行了整体评估,并对几个亚组进行了评估:年龄、性别、受伤程度(2 级或 3 级)、撕脱性骨折、使用拐杖、使用石膏。亚组之间的差异通过广义对数秩检验进行评估:结果:扭伤后 12 个月内,所有临床评分均有所改善。卡尔森评分的中位数(四分位间距)从 6 周时的 62 分(50-80 分)提高到 3 个月时的 90 分(72-100 分),6 个月时提高到 97 分(82-100 分),9 个月时提高到 100 分(90-100 分),1 年时提高到 100 分(100-100 分)。随着时间推移的积极变化分析表明,积极变化非常明显(P 值 结论):首次踝关节扭伤后的临床状况在第一年的不同时间点之间的PROMs均有显著改善。首次外侧踝关节扭伤 12 个月后,13% 的患者结果为 "一般 "或 "较差"。年龄越大和存在撕脱性骨折与恢复越慢和结果越差相关。这些信息在临床实践中非常有用,可用于预测病情的进一步发展并告知患者。此外,这些信息对改进治疗策略也很有价值:二级(前瞻性队列研究)。
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来源期刊
Foot and Ankle Surgery
Foot and Ankle Surgery ORTHOPEDICS-
CiteScore
4.60
自引率
16.00%
发文量
202
期刊介绍: Foot and Ankle Surgery is essential reading for everyone interested in the foot and ankle and its disorders. The approach is broad and includes all aspects of the subject from basic science to clinical management. Problems of both children and adults are included, as is trauma and chronic disease. Foot and Ankle Surgery is the official journal of European Foot and Ankle Society. The aims of this journal are to promote the art and science of ankle and foot surgery, to publish peer-reviewed research articles, to provide regular reviews by acknowledged experts on common problems, and to provide a forum for discussion with letters to the Editors. Reviews of books are also published. Papers are invited for possible publication in Foot and Ankle Surgery on the understanding that the material has not been published elsewhere or accepted for publication in another journal and does not infringe prior copyright.
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