Correlates of quality of life in autistic individuals

IF 2.2 4区 医学 Q1 EDUCATION, SPECIAL Research in Autism Spectrum Disorders Pub Date : 2024-05-07 DOI:10.1016/j.rasd.2024.102401
Kristen T. MacKenzie , Anabelle Theodat , Kelly B. Beck , Caitlin M. Conner , Carla A. Mazefsky , Shaun M. Eack
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Abstract

Background

Quality of life is an important outcome to autistic individuals. However, the correlates of quality of life in this population are not well known. The purpose of this project was to investigate the extent to which employment, depression, anxiety, and social participation were associated with quality of life in autistic individuals. We also explored potential associations between emotion dysregulation and quality of life.

Method

Baseline data from two randomized control trials were used for analysis. A total of 125 autistic adolescents and adults aged 16–45 (M = 25.40) participated. Linear regression models were constructed to investigate whether employment, depression, anxiety, and social participation were associated with five domains of quality of life: overall, physical health, psychological, social relationships, and environment. Additional linear regression models explored whether emotion dysregulation was associated with the same quality of life domains.

Results

Surprisingly, employment was not significantly associated with any quality of life domain. Greater depression severity was significantly associated with poorer quality of life across all domains. Greater social participation was associated with better quality of life, but only for individuals with lower anxiety. More severe dysphoria was associated with poorer overall quality of life and the psychological and physical health domains.

Conclusions

Results suggest that mental health and emotion dysregulation are important predictors of quality of life for autistic people. They also suggest that anxiety symptoms may attenuate the beneficial effects of social participation. This study provides insight into the unique experiences of autistic individuals and highlights potential unmet need.

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自闭症患者生活质量的相关因素
背景对自闭症患者来说,生活质量是一个重要的结果。然而,人们对自闭症患者生活质量的相关因素却知之甚少。本项目旨在调查就业、抑郁、焦虑和社会参与在多大程度上与自闭症患者的生活质量相关。我们还探讨了情绪失调与生活质量之间的潜在关联。方法我们使用了两项随机对照试验的基线数据进行分析。共有 125 名 16-45 岁(M=25.40)的自闭症青少年和成人参加了该试验。我们建立了线性回归模型,以研究就业、抑郁、焦虑和社会参与是否与生活质量的五个方面相关:整体、身体健康、心理、社会关系和环境。其他线性回归模型还探讨了情绪失调是否与相同的生活质量领域相关。结果出人意料的是,就业与任何生活质量领域都没有显著关联。抑郁严重程度越高,生活质量越差。更多的社会参与与更高的生活质量有关,但这只适用于焦虑程度较低的人。结果表明,心理健康和情绪失调是自闭症患者生活质量的重要预测因素。研究结果还表明,焦虑症状可能会削弱社会参与的有益影响。这项研究有助于深入了解自闭症患者的独特经历,并强调了潜在的未满足需求。
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来源期刊
CiteScore
4.20
自引率
8.00%
发文量
108
期刊介绍: Research in Autism Spectrum Disorders (RASD) publishes high quality empirical articles and reviews that contribute to a better understanding of Autism Spectrum Disorders (ASD) at all levels of description; genetic, neurobiological, cognitive, and behavioral. The primary focus of the journal is to bridge the gap between basic research at these levels, and the practical questions and difficulties that are faced by individuals with ASD and their families, as well as carers, educators and clinicians. In addition, the journal encourages submissions on topics that remain under-researched in the field. We know shamefully little about the causes and consequences of the significant language and general intellectual impairments that characterize half of all individuals with ASD. We know even less about the challenges that women with ASD face and less still about the needs of individuals with ASD as they grow older. Medical and psychological co-morbidities and the complications they bring with them for the diagnosis and treatment of ASD represents another area of relatively little research. At RASD we are committed to promoting high-quality and rigorous research on all of these issues, and we look forward to receiving many excellent submissions.
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