Influence of the Duration of Circadian Rhythm Dis-Turbance by Light Exposure on the Morphology of the Liver of Laboratory Rats

IF 0.8 4区 物理与天体物理 Q4 OPTICS Optics and Spectroscopy Pub Date : 2024-04-01 DOI:10.1134/s0030400x2310017x
S. S. Pakhomy, O. V. Zlobina, I. O. Bugaeva, G. N. Maslyakova, A. N. Ivanov, A. O. Moskvina
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Abstract

We studied the effect of long-term constant light exposure on the severity and reversibility of morphological changes in the liver of laboratory rats. Modeling of light exposure was carried out by means of 24 h exposure to artificial light (in the daytime—300 lk, at night—500 lk). During the study we found that morphological changes in the liver were represented by damage to the parenchyma and circulatory disorders, the degree of which increased with increasing duration of exposure. After providing natural light in the laboratory, gradual recovery of the morphological structure of the organ was observed, which indicates the reversibility of the changes detected.

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光照扰乱昼夜节律的持续时间对实验鼠肝脏形态的影响
摘要 我们研究了长期持续光照对实验鼠肝脏形态变化的严重性和可逆性的影响。光照模型是通过人工光照(白天-300 lk,夜间-500 lk)24 小时来建立的。在研究过程中,我们发现肝脏的形态变化表现为实质受损和循环障碍,其程度随着照射时间的延长而增加。在实验室中提供自然光后,观察到器官的形态结构逐渐恢复,这表明检测到的变化是可逆的。
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来源期刊
Optics and Spectroscopy
Optics and Spectroscopy 物理-光谱学
CiteScore
1.60
自引率
0.00%
发文量
55
审稿时长
4.5 months
期刊介绍: Optics and Spectroscopy (Optika i spektroskopiya), founded in 1956, presents original and review papers in various fields of modern optics and spectroscopy in the entire wavelength range from radio waves to X-rays. Topics covered include problems of theoretical and experimental spectroscopy of atoms, molecules, and condensed state, lasers and the interaction of laser radiation with matter, physical and geometrical optics, holography, and physical principles of optical instrument making.
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