Ia. S. Vavilina, A. A. Shpak, T. A. Druzhkova, A. B. Guekht, N. V. Gulyaeva
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引用次数: 0
Abstract
The simplicity of collecting and evaluating tear fluid (TF) can potentially provide a convenient non-invasive diagnostic tool that easily fits into a personalized approach to medicine based on risk assessment. Though, to date, most tear biomarkers are not yet ready for routine use due to problems with their clinical validation, given the huge clinical advantage of TF and the emerging advanced technical approaches developed for proteomic, lipidomic and metabolomic analysis of tears, TF studies will doubtless become a routine test for health monitoring in the near future. A number of associations between the levels of different substances in TF and the brain makes TF an invaluable source of brain disease biomarkers helpful in early diagnostics and personalized treatment. TF is a promising biological material, an invaluable source for predictive, diagnostic, prognostic, and mechanistic biomarkers.
期刊介绍：
Neurochemical Journal (Neirokhimiya) provides a source for the communication of the latest findings in all areas of contemporary neurochemistry and other fields of relevance (including molecular biology, biochemistry, physiology, neuroimmunology, pharmacology) in an afford to expand our understanding of the functions of the nervous system. The journal presents papers on functional neurochemistry, nervous system receptors, neurotransmitters, myelin, chromaffin granules and other components of the nervous system, as well as neurophysiological and clinical aspects, behavioral reactions, etc. Relevant topics include structure and function of the nervous system proteins, neuropeptides, nucleic acids, nucleotides, lipids, and other biologically active components.
The journal is devoted to the rapid publication of regular papers containing the results of original research, reviews highlighting major developments in neurochemistry, short communications, new experimental studies that use neurochemical methodology, descriptions of new methods of value for neurochemistry, theoretical material suggesting novel principles and approaches to neurochemical problems, presentations of new hypotheses and significant findings, discussions, chronicles of congresses, meetings, and conferences with short presentations of the most sensational and timely reports, information on the activity of the Russian and International Neurochemical Societies, as well as advertisements of reagents and equipment.
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