Navigating the diagnostic maze: A case presentation of C1q vasculitis mimicking hypocomplementemic urticarial vasculitis in a patient with systemic lupus erythematosus.

IF 1.9 4区 医学 Q3 RHEUMATOLOGY Lupus Pub Date : 2024-07-01 Epub Date: 2024-05-08 DOI:10.1177/09612033241253156
Veronica Castellanos-Molina, Alejandra Gomez, Maddy Mejía, Alejandra Toquica, Santiago Bernal-Macías
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Abstract

In rare instances, patients with SLE may exhibit atypical clinical manifestations, such as Hypocomplementemic Urticarial Vasculitis, which can pose diagnostic challenges. Here, we present a case report of a 28-year-old female with a history of SLE with lupus nephritis clase IV who developed HUV-like symptoms, ultimately leading to a diagnosis of C1q Vasculitis. This case underscores the importance of considering C1q Vasculitis in SLE patients presenting with HUV-like features and highlights Rituximab as a promising therapeutic option for managing this rare condition.

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穿越诊断迷宫:系统性红斑狼疮患者模仿低补体荨麻疹性血管炎的 C1q 血管炎病例。
在极少数情况下,系统性红斑狼疮患者可能会表现出不典型的临床表现,如低补体性荨麻疹性血管炎,这给诊断带来了挑战。在此,我们报告了一例28岁女性系统性红斑狼疮患者的病例,该患者有系统性红斑狼疮合并狼疮性肾炎IV期病史,并出现HUV样症状,最终被诊断为C1q血管炎。本病例强调了在系统性红斑狼疮患者出现 HUV 样特征时考虑 C1q 血管炎的重要性,并突出了利妥昔单抗是治疗这种罕见病的一种有前途的治疗方案。
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来源期刊
Lupus
Lupus 医学-风湿病学
CiteScore
4.20
自引率
11.50%
发文量
225
审稿时长
1 months
期刊介绍: The only fully peer reviewed international journal devoted exclusively to lupus (and related disease) research. Lupus includes the most promising new clinical and laboratory-based studies from leading specialists in all lupus-related disciplines. Invaluable reading, with extended coverage, lupus-related disciplines include: Rheumatology, Dermatology, Immunology, Obstetrics, Psychiatry and Cardiovascular Research…
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