Posterior Reversible Encephalopathy Syndrome in Children and Adolescents.

IF 3.9 2区 医学 Q1 PERIPHERAL VASCULAR DISEASE Current Hypertension Reports Pub Date : 2024-08-01 Epub Date: 2024-05-10 DOI:10.1007/s11906-024-01303-6
Susan M Halbach, Deborah Stein
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Abstract

Purpose of review: Posterior reversible encephalopathy syndrome, or PRES, is a constellation of severe, acute hypertension and specific brain imaging findings. This may be caused by failure of the cerebral autoregulatory system to manage acute or severe changes in blood pressure. The incidence in children is unknown but estimated to be more common in children with predisposing factors including renal disease, autoimmune disease, malignancy, solid organ transplantation, stem cell transplantation, hypertension, sepsis, and exposure to certain medications.

Recent findings: Management of PRES includes addressing hypertension, removing offending agents when possible, and anti-epileptic medications. Most children with PRES recover completely, but recurrence is possible. Lack of resolution of imaging findings likely portends a worse prognosis.

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儿童和青少年后可逆性脑病综合征。
审查目的:后可逆性脑病综合征(PRES)是由严重的急性高血压和特殊的脑成像结果组成的症候群。其原因可能是大脑自动调节系统无法控制血压的急性或严重变化。在儿童中的发病率尚不清楚,但估计在有易感因素(包括肾脏疾病、自身免疫性疾病、恶性肿瘤、实体器官移植、干细胞移植、高血压、败血症和接触某些药物)的儿童中更为常见:治疗 PRES 的方法包括治疗高血压、尽可能去除致病因子和服用抗癫痫药物。大多数患有 PRES 的儿童可完全康复,但也有可能复发。影像学检查结果不明显可能预示着预后较差。
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来源期刊
Current Hypertension Reports
Current Hypertension Reports 医学-外周血管病
CiteScore
10.50
自引率
0.00%
发文量
65
审稿时长
6-12 weeks
期刊介绍: This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of hypertension. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as antihypertensive therapies, associated metabolic disorders, and therapeutic trials. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.
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