GPs’ practices when prescribing buprenorphine in primary care: A survey among the Sentinelles network

IF 2.2 4区 医学 Q3 PHARMACOLOGY & PHARMACY Therapie Pub Date : 2024-11-01 DOI:10.1016/j.therap.2024.04.002
Barbara Lépine , Marion Debin , Lise Dassieu , Laetitia Gimenez , Aurore Palmaro , Camille Ponté , Morgane Swital , Maryse Lapeyre-Mestre , Thierry Blanchon , Julie Dupouy
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Abstract

Introduction

France is a leading country for opioid agonist treatment providing, with a predominance of buprenorphine. General practitioners (GPs) are the main prescribers of buprenorphine, but they seem to be less involved over the last 10 years. This work is the second part of a larger study analysing buprenorphine prescribing among French GPs working in primary care, and aims to describe GPs’ practices when prescribing buprenorphine.

Methods

This is a cross-sectional study conducted in France from March to July 2021 among a sample of GPs in the Sentinelles network, a national epidemiologic surveillance system. Data about the last situations of initiation and renewal of buprenorphine were collected.

Results

Among the 237 participants (34.3% response rate), 156 responded to the questionnaire about the last situation of renewal and 41 about the last situation of initiation. The last initiation occurred more than 12 months earlier for 46.3% of respondents, whereas the last renewal occurred less than 1 month ago for 68.6%. There was an over-representation of the male gender among the patients who were consulting (initiation 70.7%, renewal 68.6%). A majority of patients had an illicit opioid use disorder (initiation 78.0%, renewal 82.7%). Overall, GPs were involved in the general care of patients with opioids use disorder and in opioids harm reduction (initiation 87.8% and 82.9%, renewal 88.5% and 51.9%).

Conclusion

Among buprenorphine prescribers, initiations were infrequent unlike renewals and involved mainly illicit opioid users.
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全科医生在初级保健中开具丁丙诺啡处方时的做法:Sentinelles 网络调查。
简介法国是提供阿片类激动剂治疗的主要国家,其中以丁丙诺啡为主。全科医生(GPs)是丁丙诺啡的主要处方者,但在过去 10 年中,他们的参与程度似乎有所降低。本研究是一项大型研究的第二部分,该研究分析了法国全科医生在基层医疗机构开具丁丙诺啡处方的情况,旨在描述全科医生在开具丁丙诺啡处方时的做法:这是一项横断面研究,于 2021 年 3 月至 7 月在法国进行,研究对象是全国流行病监测系统 Sentinelles 网络中的全科医生样本。研究收集了有关丁丙诺啡最后一次使用和续用情况的数据:在 237 名参与者(回复率为 34.3%)中,有 156 人回复了关于最后一次续用情况的问卷,41 人回复了关于最后一次开始使用情况的问卷。46.3%的受访者最后一次开始使用是在 12 个月之前,而 68.6%的受访者最后一次续用是在不到 1 个月之前。在接受咨询的患者中,男性比例较高(初次咨询 70.7%,再次咨询 68.6%)。大多数患者患有非法阿片类药物使用障碍(开始就诊的占 78.0%,续诊的占 82.7%)。总体而言,全科医生参与了对阿片类药物使用障碍患者的一般护理和减少阿片类药物危害的工作(开始87.8%和82.9%,延续88.5%和51.9%):结论:在丁丙诺啡处方者中,与续用不同,启动处方的情况并不常见,而且主要涉及非法阿片类药物使用者。
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来源期刊
Therapie
Therapie 医学-药学
CiteScore
3.50
自引率
7.70%
发文量
132
审稿时长
57 days
期刊介绍: Thérapie is a peer-reviewed journal devoted to Clinical Pharmacology, Therapeutics, Pharmacokinetics, Pharmacovigilance, Addictovigilance, Social Pharmacology, Pharmacoepidemiology, Pharmacoeconomics and Evidence-Based-Medicine. Thérapie publishes in French or in English original articles, general reviews, letters to the editor reporting original findings, correspondence relating to articles or letters published in the Journal, short articles, editorials on up-to-date topics, Pharmacovigilance or Addictovigilance reports that follow the French "guidelines" concerning good practice in pharmacovigilance publications. The journal also publishes thematic issues on topical subject. The journal is indexed in the main international data bases and notably in: Biosis Previews/Biological Abstracts, Embase/Excerpta Medica, Medline/Index Medicus, Science Citation Index.
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