Review: The Role of Dual-Energy Computed Tomography in Detecting Monosodium Urate Deposits in Vascular Tissues.

IF 5.7 2区医学 Q1 RHEUMATOLOGY Current Rheumatology Reports Pub Date : 2024-08-01 Epub Date: 2024-05-13 DOI:10.1007/s11926-024-01151-y

Julia Held, David Haschka, Pietro G Lacaita, Gudrun M Feuchtner, Werner Klotz, Hannes Stofferin, Christina Duftner, Günter Weiss, Andrea S Klauser

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Abstract

Purpose of review: To highlight novel findings in the detection of monosodium urate deposits in vessels using dual energy computed tomography, and to discuss the potential clinical implications for gout and hyperuricemia patients.

Recent findings: Gout is an independent risk factor for cardiovascular disease. However, classical risk calculators do not take into account these hazards, and parameters to identify patients at risk are lacking. Monosodium urate measured by dual energy computed tomography is a well-established technology for the detection and quantification of monosodium urate deposits in peripheral joints and tendons. Recent findings also suggest its applicability to identify vascular urate deposits. Dual energy computed tomography is a promising tool for detection of cardiovascular monosodium urate deposits in gout patients, to better delineate individuals at increased risk for cardiovascular disease.

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回顾：双能量计算机断层扫描在检测血管组织中尿酸单钠沉积物中的作用。

综述的目的：重点介绍利用双能计算机断层扫描检测血管中单钠尿酸盐沉积的新发现，并讨论其对痛风和高尿酸血症患者的潜在临床意义：痛风是心血管疾病的独立风险因素。最新研究结果：痛风是心血管疾病的独立危险因素，但传统的风险计算器并没有考虑到这些危害，也缺乏识别高危患者的参数。通过双能计算机断层扫描测量尿酸单钠是一项成熟的技术，可用于检测和量化外周关节和肌腱中的尿酸单钠沉积物。最近的研究结果还表明，该技术可用于识别血管尿酸盐沉积。双能计算机断层扫描是检测痛风患者心血管中单钠尿酸盐沉积的一种很有前途的工具，可以更好地确定心血管疾病风险增加的人群。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Rheumatology Reports RHEUMATOLOGY-

CiteScore

11.20

自引率

0.00%

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期刊介绍： This journal aims to review the most important, recently published research in the field of rheumatology. By providing clear, insightful, balanced contributions by international experts, the journal intends to serve all those involved in the care and prevention of rheumatologic conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas such as the many forms of arthritis, osteoporosis and metabolic bone disease, and systemic lupus erythematosus. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also occasionally provided.