Case Report on Botulinum Toxin Treatment for Complex Regional Pain Syndrome in a Digit Reconstruction.

R Rashaan, P T Arkoumanis, C Gakis, F A Lyssiotis, J Michalis, P Anagnostopoulos, K Stratakis
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Abstract

Objective:To evaluate subcutaneous Botulinum toxin type A (BTX-A) efficacy in alleviating severe allodynia in complex regional pain syndrome (CRPS) type II post-digit reconstruction. Methods: After surgical debridement and flap reconstruction for post-traumatic necrosis, a CRPS type II patient received subcutaneous BTX-A. Assessments tracked symptom changes and daily life improvements. Discussion:There are various CRPS management modalities, including rehabilitation and pharmacology. The limited efficacy of conventional non-steroidal antiinflammatory drugs contrasts with promising subcutaneous BTX-A, offering rapid pain relief. Conclusion:Our case underscores the efficacy of subcutaneous BTX-A in CRPS type II, prompting further research and safe outpatient protocol development.

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肉毒杆菌毒素治疗复发性区域疼痛综合征的病例报告。
目的:评估皮下注射A型肉毒杆菌毒素(BTX-A)对缓解复杂性区域疼痛综合征(CRPS)II型趾骨重建术后严重异感症的疗效。治疗方法一名 II 型 CRPS 患者在因创伤后坏死而进行手术清创和皮瓣重建后,接受了皮下 BTX-A。评估跟踪了症状变化和日常生活改善情况。讨论:CRPS的治疗方法多种多样,包括康复治疗和药物治疗。传统的非甾体抗炎药物疗效有限,而皮下注射BTX-A可迅速缓解疼痛,两者形成鲜明对比。结论:我们的病例强调了皮下BTX-A对CRPS II型的疗效,促使我们进一步开展研究并制定安全的门诊方案。
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