Reducing potentially inappropriate polypharmacy at a national and international level: the impact of deprescribing networks.

IF 3.6 3区 医学 Q2 PHARMACOLOGY & PHARMACY Expert Review of Clinical Pharmacology Pub Date : 2024-05-01 Epub Date: 2024-05-20 DOI:10.1080/17512433.2024.2355270
Emily G McDonald, Carina Lundby, Wade Thompson, Cynthia Boyd, Barbara Farrell, Camille Gagnon, Jennie Herbin, Ninh Khuong, Frank Moriarty, Tiphaine Pierson, Sion Scott, Ian A Scott, Jim Silvius, Anne Spinewine, Michael A Steinman, Cara Tannenbaum, Johanna Trimble, Justin P Turner, Emily Reeve
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Abstract

Introduction: Over the past decade, polypharmacy has increased dramatically. Measurable harms include falls, fractures, cognitive impairment, and death. The associated costs are massive and contribute substantially to low-value health care. Deprescribing is a promising solution, but there are barriers. Establishing a network to address polypharmacy can help overcome barriers by connecting individuals with an interest and expertise in deprescribing and can act as an important source of motivation and resources.

Areas covered: Over the past decade, several deprescribing networks were launched to help tackle polypharmacy, with evidence of individual and collective impact. A network approach has several advantages; it can spark interest, ideas and enthusiasm through information sharing, meetings and conversations with the public, providers, and other key stakeholders. In this special report, the details of how four deprescribing networks were established across the globe are detailed.

Expert opinion: Networks create links between people who lead existing and/or budding deprescribing practices and policy initiatives, can influence people with a shared passion for deprescribing, and facilitate sharing of intellectual capital and tools to take initiatives further and strengthen impact.This report should inspire others to establish their own deprescribing networks, a critical step in accelerating a global deprescribing movement.

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在国家和国际层面减少潜在的不当多药使用:处方网络的影响。
导言:在过去的十年中,多种药物的使用急剧增加。可衡量的危害包括跌倒、骨折、认知障碍和死亡。与此相关的成本巨大,大大增加了医疗保健的低价值。取消处方是一个很有前景的解决方案,但也存在障碍。建立一个网络来解决多药疗法问题,可以将对去处方化感兴趣并具有相关专业知识的个人联系起来,从而帮助克服障碍,并成为动力和资源的重要来源:在过去十年中,有几个去药瘾网络已经启动,以帮助解决多药滥用问题,有证据表明它们对个人和集体都产生了影响。网络方法有几个优势:它可以通过与公众、医疗服务提供者和其他主要利益相关者共享信息、举行会议和对话,激发他们的兴趣、想法和热情。在本特别报告中,将详细介绍如何在全球范围内建立四个去处方化网络:网络在领导现有和/或萌芽中的去处方化实践和政策倡议的人们之间建立了联系,可以影响对去处方化有共同热情的人们,并促进知识资本和工具的共享,以进一步推动倡议的实施并加强其影响力。
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来源期刊
Expert Review of Clinical Pharmacology
Expert Review of Clinical Pharmacology PHARMACOLOGY & PHARMACY-
CiteScore
7.30
自引率
2.30%
发文量
127
期刊介绍: Advances in drug development technologies are yielding innovative new therapies, from potentially lifesaving medicines to lifestyle products. In recent years, however, the cost of developing new drugs has soared, and concerns over drug resistance and pharmacoeconomics have come to the fore. Adverse reactions experienced at the clinical trial level serve as a constant reminder of the importance of rigorous safety and toxicity testing. Furthermore the advent of pharmacogenomics and ‘individualized’ approaches to therapy will demand a fresh approach to drug evaluation and healthcare delivery. Clinical Pharmacology provides an essential role in integrating the expertise of all of the specialists and players who are active in meeting such challenges in modern biomedical practice.
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