The role of automated insulin delivery technology in diabetes.

IF 8.4 1区 医学 Q1 ENDOCRINOLOGY & METABOLISM Diabetologia Pub Date : 2024-10-01 Epub Date: 2024-05-13 DOI:10.1007/s00125-024-06165-w
Charlotte K Boughton, Roman Hovorka
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Abstract

The role of automated insulin delivery systems in diabetes is expanding. Hybrid closed-loop systems are being used in routine clinical practice for treating people with type 1 diabetes. Encouragingly, real-world data reflects the performance and usability observed in clinical trials. We review the commercially available hybrid closed-loop systems, their distinctive features and the associated real-world data. We also consider emerging indications for closed-loop systems, including the treatment of type 2 diabetes where variability of day-to-day insulin requirements is high, and other challenging applications for this technology. We discuss issues around access and implementation of closed-loop technology, and consider the limitations of present closed-loop systems, as well as innovative approaches that are being evaluated to improve their performance.

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胰岛素自动输送技术在糖尿病中的作用。
胰岛素自动给药系统在糖尿病中的作用正在不断扩大。混合闭环系统正被用于治疗 1 型糖尿病患者的常规临床实践中。令人鼓舞的是,实际数据反映了临床试验中观察到的性能和可用性。我们回顾了市面上销售的混合闭环系统、它们的显著特点以及相关的真实世界数据。我们还考虑了闭环系统的新兴适应症,包括治疗日常胰岛素需求变化较大的 2 型糖尿病,以及该技术的其他具有挑战性的应用。我们讨论了与闭环技术的获取和实施有关的问题,并考虑了现有闭环系统的局限性,以及为提高其性能而正在评估的创新方法。
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来源期刊
Diabetologia
Diabetologia 医学-内分泌学与代谢
CiteScore
18.10
自引率
2.40%
发文量
193
审稿时长
1 months
期刊介绍: Diabetologia, the authoritative journal dedicated to diabetes research, holds high visibility through society membership, libraries, and social media. As the official journal of the European Association for the Study of Diabetes, it is ranked in the top quartile of the 2019 JCR Impact Factors in the Endocrinology & Metabolism category. The journal boasts dedicated and expert editorial teams committed to supporting authors throughout the peer review process.
期刊最新文献
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