[Consequence of hypertensive disorders during pregnancy (THE) on women's cardiovascular health].

IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-05-13 DOI:10.1016/j.hipert.2024.04.005
W G Espeche, P Carrera Ramos, J Minetto, D Gomez, A De Iraola, G R Cerri, M R Salazar
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Abstract

Patients with hypertensive disorders of pregnancy (HDP) are at increased risk of maternal-fetal complications and represent the third leading cause of maternal mortality. To date, it is known that women experiencing this condition during pregnancy have a higher future risk of cardiovascular events (CVD). Our objective was to report the incidence of new-onset hypertension in the postpartum period. We conducted a cohort study in high-risk pregnant patients who underwent ambulatory blood pressure monitoring (ABPM) between weeks 20-30. Patients were categorized as normotensive (NT) or gestational hypertensive (GH), excluding those with chronic hypertension, and were followed until the end of pregnancy with a postpartum assessment after 3months. Patients with HDP (39%) had a higher incidence of preeclampsia and newborns with low birth weight and preterm birth. A total of 177 pregnant women were analyzed for the primary outcome. Among those with GH, 33.3% vs 17.2% of NT (P=.014) reported new-onset hypertension. The odds ratio for developing new-onset hypertension was 2.3 (95%CI: 1.20-4.77), for those with GH. In conclusion, pregnant patients with GH assessed by ABPM between 20-30weeks are at higher risk of developing new-onset hypertension in the postpartum period, emphasizing the need for closer monitoring and control to prevent future cardiovascular complications.

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[妊娠期高血压疾病(THE)对妇女心血管健康的影响]。
妊娠期高血压疾病(HDP)患者发生母胎并发症的风险增加,是导致孕产妇死亡的第三大原因。迄今为止,人们已经知道,在妊娠期间患有这种疾病的妇女未来发生心血管事件(CVD)的风险较高。我们的目的是报告产后新发高血压的发病率。我们对在怀孕 20-30 周期间接受动态血压监测 (ABPM) 的高危孕妇进行了一项队列研究。患者被分为血压正常(NT)和妊娠高血压(GH)两类,其中不包括慢性高血压患者,随访至妊娠结束,并在产后 3 个月进行评估。妊娠高血压患者(39%)的子痫前期、新生儿低出生体重和早产的发生率较高。共有 177 名孕妇接受了主要结果分析。在患有 GH 的孕妇中,33.3%(P=0.014)与 17.2%(P=0.014)的 NT 孕妇报告了新发高血压。GH患者新发高血压的几率比为2.3(95%CI:1.20-4.77)。总之,在20-30周期间接受ABPM评估的GH孕妇在产后罹患新发高血压的风险较高,这强调了更密切监测和控制以预防未来心血管并发症的必要性。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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