Research progress on the polysaccharide extraction and antibacterial activity

IF 3 4区 生物学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY Annals of Microbiology Pub Date : 2024-05-11 DOI:10.1186/s13213-024-01762-x
Lihui Liang, Qihang Su, Yu Ma, Shuzhen Zhao, Huanjie Zhang, Xiaofeng Gao
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Abstract

Over time, the amount of germs resistant to antibacterial medications has been steadily rising because of their prolonged and indiscriminate use. The increase in drug resistance significantly threatens to human health and has become a globally recognized issue of concern. Therefore, identifying new antibacterial drugs is urgently needed. Polysaccharides are natural macromolecular substances that exist in plants, microorganisms, and animals, They have an immense amount of use in the food and medical industries. Polysaccharides can be categorized as plant, animal, or microbial based on the sources of the polysaccharides. Polysaccharides are natural compounds with antibacterial properties that exerts antibacterial activity by disrupting bacterial cell walls and cell membranes. They show potential as candidates for the creation and application of novel antibiotics. This article reviews the classification of polysaccharides, their isolation and purification, mechanisms of action, and antibacterial activity. The primary objective of this study is to lay down an empirical groundwork for examining the antibacterial properties of polysaccharides.
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多糖提取和抗菌活性的研究进展
随着时间的推移,由于长期滥用抗菌药物,对抗菌药物产生抗药性的病菌数量在稳步上升。耐药性的增加严重威胁人类健康,已成为全球公认的关注问题。因此,寻找新的抗菌药物迫在眉睫。多糖是存在于植物、微生物和动物中的天然大分子物质,在食品和医药行业有着巨大的用途。根据多糖的来源,可将多糖分为植物多糖、动物多糖和微生物多糖。多糖是具有抗菌特性的天然化合物,通过破坏细菌细胞壁和细胞膜来发挥抗菌活性。多糖具有开发和应用新型抗生素的潜力。本文综述了多糖的分类、分离和纯化、作用机制和抗菌活性。本研究的主要目的是为研究多糖的抗菌特性奠定经验基础。
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来源期刊
Annals of Microbiology
Annals of Microbiology 生物-生物工程与应用微生物
CiteScore
6.40
自引率
0.00%
发文量
41
审稿时长
3.2 months
期刊介绍: Annals of Microbiology covers these fields of fundamental and applied microbiology: general, environmental, food, agricultural, industrial, ecology, soil, water, air and biodeterioration. The journal’s scope does not include medical microbiology or phytopathological microbiology. Papers reporting work on bacteria, fungi, microalgae, and bacteriophages are welcome. Annals of Microbiology publishes Review Articles, Original Articles, Short Communications, and Editorials. Originally founded as Annali Di Microbiologia Ed Enzimologia in 1940, Annals of Microbiology is an official journal of the University of Milan.
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