The Surgical Management of the Mesentery in Crohn's Disease

IF 1.2 4区 医学 Q4 GASTROENTEROLOGY & HEPATOLOGY Clinics in Colon and Rectal Surgery Pub Date : 2024-05-10 DOI:10.1055/s-0044-1786197
J.C. Coffey, M.L. Devine
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Abstract

Increasing evidence suggests that Crohn's disease is a primary mesenteropathy and that resection of the mesentery, or its exclusion from an anastomosis, may alter disease progression. If borne out in clinical trials, this observation would be welcome, as current pharmacotherapeutic approaches to Crohn's disease appear to have limited effect on disease progression. This article explores arguments for and against the alteration of mesenteric inputs by surgical means, in Crohn's disease.

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克罗恩病肠系膜的手术治疗
越来越多的证据表明,克罗恩病是一种原发性肠系膜病,切除肠系膜或将其排除在吻合口之外可能会改变疾病的进展。如果在临床试验中得到证实,这一观点将受到欢迎,因为目前治疗克罗恩病的药物疗法似乎对疾病进展的影响有限。本文探讨了支持和反对通过外科手术改变克罗恩病肠系膜输入的观点。
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来源期刊
Clinics in Colon and Rectal Surgery
Clinics in Colon and Rectal Surgery GASTROENTEROLOGY & HEPATOLOGYSURGERY-SURGERY
CiteScore
2.60
自引率
7.10%
发文量
84
期刊介绍: Clinics in Colon and Rectal Surgery is a review journal that publishes topic-specific issues on diseases of the small bowel, colon, rectum, and anus. Designed for clinicians, researchers, and educators involved with diseases of the intestinal tract, the journal covers a broad spectrum of basic information, controversial clinical issues, and established and innovative diagnostic techniques. Issue topics comprehensively cover the entire specialty over a 3-4 year period, allowing the articles to serve as study material for educational programs and certifying examinations. The inclusion of research and clinical material also allows physicians to remain knowledgeable of current advances in the specialty.
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