{"title":"Change in Chromatographic Parameters of Some Phenylpropanoids in Different Mobile Phases Under Reversed-Phase HPLC Conditions","authors":"O. K. Abramov, A. F. Ryabukha, I. V. Pletneva","doi":"10.1007/s11094-024-03128-8","DOIUrl":null,"url":null,"abstract":"<p>The effect of the eluent composition (type and concentration of the organic and acid components) on the retention times and selectivity of the separation of some standard samples of phenylpropanoids under reversed- phase HPLC conditions is studied. Ethanol, being a nontoxic solvent, exhibited good characteristics as an eluent for the separation of this group of substances. A mobile phase containing ethanol and organic acids could be recommended as an extractant for studies of plant raw material containing phenylpropanoids.</p>","PeriodicalId":19990,"journal":{"name":"Pharmaceutical Chemistry Journal","volume":"59 1","pages":""},"PeriodicalIF":0.8000,"publicationDate":"2024-05-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Pharmaceutical Chemistry Journal","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s11094-024-03128-8","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
引用次数: 0
Abstract
The effect of the eluent composition (type and concentration of the organic and acid components) on the retention times and selectivity of the separation of some standard samples of phenylpropanoids under reversed- phase HPLC conditions is studied. Ethanol, being a nontoxic solvent, exhibited good characteristics as an eluent for the separation of this group of substances. A mobile phase containing ethanol and organic acids could be recommended as an extractant for studies of plant raw material containing phenylpropanoids.
期刊介绍：
Pharmaceutical Chemistry Journal is a monthly publication devoted to scientific and technical research on the creation of new drugs and the improvement of manufacturing technology of drugs and intermediates. International contributors cover the entire spectrum of new drug research, including:
methods of synthesis;
results of pharmacological, toxicological, and biochemical studies;
investigation of structure - activity relationships in prediction of new compounds;
methods and technical facilities used; and
problems associated with the development of ecologically safe and economically feasible methods of industrial production.
In addition, analytical reviews of the international literature in the field provide coverage of the most recent developments around the world.
Pharmaceutical Chemistry Journal is a translation of the Russian journal Khimiko-Farmatsevticheskii Zhurnal. The Russian Volume Year is published in English from April.
All articles are peer-reviewed.
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