Menglin Chen, Houshu Tu, Jiaoli Zhou, Yi Zhang, Shuting Wen, Yao Xiao, Ling He
{"title":"The causal correlation between gastroesophageal reflux disease and chronic widespread pain: a bidirectional mendelian randomization study","authors":"Menglin Chen, Houshu Tu, Jiaoli Zhou, Yi Zhang, Shuting Wen, Yao Xiao, Ling He","doi":"10.1101/2024.05.06.24306927","DOIUrl":null,"url":null,"abstract":"<strong>Background</strong> Previous observational research found a relationship between gastroesophageal reflux disease (GERD) and chronic widespread pain (CWP). Despite this, it is unknown which, if any, of the conditions produces the other. Our study will use bidirectional Mendelian randomization (MR) to evaluate their causal link.","PeriodicalId":501258,"journal":{"name":"medRxiv - Gastroenterology","volume":"100 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"medRxiv - Gastroenterology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1101/2024.05.06.24306927","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Background Previous observational research found a relationship between gastroesophageal reflux disease (GERD) and chronic widespread pain (CWP). Despite this, it is unknown which, if any, of the conditions produces the other. Our study will use bidirectional Mendelian randomization (MR) to evaluate their causal link.