Sara Mahdjoub, Chamseddine Derabli, Muhammet Yildirim, Raouf Boulcina, Abdelmadjid Debache
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引用次数: 0
Abstract
In this study, a highly effective microwave-assisted method employing a multicomponent domino Knoevenagel/phospha-Michael reaction has been established. This approach facilitates the synthesis of a novel set of pyrazolylphosphonate derivatives in good yields by combining aryl aldehydes with pyrazolones and trialkylphosphites, utilizing piperidine as a Bronsted base catalyst. All pyrazolylphosphonates have been characterized by means of IR, 1H-NMR, 13C-NMR, and HRMS analyses and physical methods. This protocol can be characterized by its eco-friendly nature, exceptional efficiency in terms of product yields, and short reaction times.
期刊介绍：
The Journal of Heterocyclic Chemistry is interested in publishing research on all aspects of heterocyclic chemistry, especially development and application of efficient synthetic methodologies and strategies for the synthesis of various heterocyclic compounds. In addition, Journal of Heterocyclic Chemistry promotes research in other areas that contribute to heterocyclic synthesis/application, such as synthesis design, reaction techniques, flow chemistry and continuous processing, multiphase catalysis, green chemistry, catalyst immobilization and recycling.
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