Efficacy and Safety of Nasal High-Frequency Oscillation in Preventing Intubation in Very-Low-Birth-Weight Infants with Respiratory Distress Syndrome

Buu Quoc Dang, Tam Thi Thanh Pham, Duc Ninh Nguyen, Nguyen Phuoc Long, Tinh Thu Nguyen
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Abstract

Background Invasive mechanical ventilation in very-low-birth-weight infants (VLBWI) was associated with immediate and long-term complications. Nasal high-frequency oscillation (nHFO) has recently become a new non-invasive ventilation (NIV) mode for treating respiratory failure in VLBWI. This study aimed to investigate the safety and efficacy of nHFO as an alternative respiratory support to prevent intubation in VLBWI who have failed other NIV modes.
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鼻腔高频振荡对预防呼吸窘迫综合征极低出生体重儿插管的有效性和安全性
背景极低出生体重儿(VLBWI)的侵入性机械通气与近期和远期并发症有关。最近,鼻腔高频振荡(nHFO)已成为治疗极低出生体重儿呼吸衰竭的一种新的无创通气(NIV)模式。本研究旨在探讨鼻腔高频振荡作为一种替代性呼吸支持手段的安全性和有效性,以防止其他无创通气模式失败的低体重儿插管。
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