Overexpression of miR-3168 impairs angiogenesis in Pulmonary Arterial Hypertension: Insights from circulating miRNA analysis

Mauro Lago-Docampo, Ainhoa Iglesias-López, Carlos Vilariño, Adolfo Baloira, Joan Albert Barberá, Isabel Blanco, Diana Valverde
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Abstract

Background Pulmonary Arterial Hypertension (PAH) is a rare disease where the thickening of the precapillary pulmonary arteries ends up inducing right heart failure. Nowadays, obtaining an early diagnosis is challenging and typically delayed until undergoing right-heart catheterization.
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过表达 miR-3168 会损害肺动脉高压的血管生成:循环 miRNA 分析的启示
背景 肺动脉高压(PAH)是一种罕见疾病,由于毛细血管前肺动脉增厚,最终导致右心衰竭。如今,要获得早期诊断非常困难,通常要等到接受右心导管检查后才能确诊。
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