Step by step technique of Stentless Florence Robotic Intracorporeal Neobladder (FloRIN), does the ureteral management influence functional outcomes?

IF 0.8 Q4 UROLOGY & NEPHROLOGY Urologia Journal Pub Date : 2024-08-01 Epub Date: 2024-05-16 DOI:10.1177/03915603241252908
Luca Lambertini, Fabrizio Di Maida, Anna Cadenar, Antonio Andrea Grosso, Francesca Valastro, Mara Bacchiani, Sofia Giudici, Alessandro Sandulli, Filippo Lipparini, Vincenzo Salamone, Daniele Paganelli, Simone Coco, Andrea Mari, Andrea Minervini
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Abstract

Introduction: Benefits and harms of avoid the sent placement during IntraCorporeal Neobladder configuration are still debated. Our objective was to describe the step-by-step technique of Florence intracorporeal neobladder (FloRIN) configuration performed with stentless procedure focusing on perioperative and mid-term functional outcomes.

Materials and methods: In this single institution prospective randomized 1:1 series all consecutive patients underwent Robot-Assisted Radical Cystectomy (RARC) and FloRIN reconfiguration from January 2021 to March 2021 were enrolled. Functional perioperative and mid-term outcomes were gathered. Postoperative complications were graded according to Clavien-Dindo classification and divided in early (<30 days from discharge) and delayed (>30 days).

Results: Overall, 10 patients were included in the analysis. Of these, the 50.0% was treated with Stentless FloRIN. In terms of baseline features, no differences were recorded between the two groups. Median age was 65 and 66 years while median BMI was 27 and 25 in the stentless and in the stent group, respectively. Concerning intraoperative variables, no intraoperative complications as well as open conversion occurred among both groups. As regard introperative features, a shorter console time was associated with stentless procedure (331 min vs 365 min). In terms of perioperative outcomes, canalization and time to drainage removal didn't differ between groups while length of hospital stay was significantly lower in stentless group 10 days versus 14 days. Early and delayed postoperative complication rate was not influenced by the ureteral management at a preliminary assessment with comparable rates of Clavien Dindo ⩾ 3a between the two groups. Mid-term functional outcomes did not differ between groups in terms of kidney function loss.

Conclusions: FloRIN with Stentless technique showed functional and perioperative preliminary outcomes comparable with the standard ureteral management strategy. Further series with longer functional follow-up assessment will be needed to confirm our preliminary results.

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无支架佛罗伦萨机器人体外新膀胱(FloRIN)的逐步技术,输尿管管理是否会影响功能结果?
导言:在体腔内新膀胱配置过程中避免送入膀胱的利弊仍存在争议。我们的目的是逐步描述采用无支架手术的佛罗伦萨体腔内新膀胱(FloRIN)配置技术,重点关注围手术期和中期功能预后:在这一单机构前瞻性随机1:1系列研究中,2021年1月至2021年3月期间接受机器人辅助根治性膀胱切除术(RARC)和FloRIN重新配置术的所有连续患者均被纳入研究。收集了围手术期和中期的功能性结果。术后并发症根据 Clavien-Dindo 分类进行分级,并按早期(30 天)进行划分:结果:共有 10 名患者纳入分析。结果:共有 10 名患者纳入分析,其中 50.0% 接受了无支架 FloRIN 治疗。就基线特征而言,两组患者没有差异。无支架组和支架组的中位年龄分别为 65 岁和 66 岁,中位体重指数分别为 27 和 25。在术中变量方面,两组患者均未出现术中并发症和开放性转流。在手术导入方面,无支架手术的控制台时间更短(331 分钟对 365 分钟)。在围手术期结果方面,两组的管道通畅率和引流清除时间没有差异,而无支架组的住院时间明显较短,为10天对14天。初步评估显示,术后早期和延迟并发症发生率不受输尿管处理方法的影响,两组患者的 Clavien Dindo ⩾ 3a 发生率相当。在肾功能丧失方面,两组的中期功能结果没有差异:采用无支架技术的 FloRIN 在功能和围手术期的初步结果与标准输尿管管理策略相当。要证实我们的初步结果,还需要进行更长时间的功能随访评估。
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来源期刊
Urologia Journal
Urologia Journal UROLOGY & NEPHROLOGY-
CiteScore
0.60
自引率
12.50%
发文量
66
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