Osteosarcoma with widespread metastasis in a 1-year-old crossbred rabbit.

IF 1.3 2区 农林科学 Q2 VETERINARY SCIENCES Veterinary Radiology & Ultrasound Pub Date : 2024-09-01 Epub Date: 2024-05-16 DOI:10.1111/vru.13385
Gordon Lye, Keren Dittmer, Sarah Pemberton, Kezia Lockhart, Rachel Pollard
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Abstract

A 14-month-old female spayed, small crossbred rabbit presented for assessment of a small, hard subcutaneous nodule in the right axilla. Serum biochemistry showed markedly increased serum ALP activity. A whole-body CT revealed an aggressive, monostotic osteolytic, and productive lesion within the left alveolar process of the maxilla, with erosion of the alveolar bone and secondary premolar depression. Innumerable metastatic osseous masses were present throughout the body, including cerebral, pulmonary, hepatic, subcutaneous, and skeletal muscular metastases. Postmortem findings confirmed widespread, metastatic osteosarcoma, with the primary lesion within the left maxilla.

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一只 1 岁大的杂交兔患骨肉瘤并广泛转移。
一只 14 个月大的雌性绝育小型杂交兔因右侧腋窝出现皮下小硬结而前来就诊。血清生化检查显示血清 ALP 活性明显升高。全身 CT 显示,上颌骨左侧牙槽突内有一个侵袭性、单层溶骨性和生产性病变,牙槽骨被侵蚀,继发前磨牙凹陷。全身出现无数转移性骨块,包括脑、肺、肝、皮下和骨骼肌肉转移。尸检结果证实了广泛转移性骨肉瘤,原发病灶位于左上颌骨。
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来源期刊
Veterinary Radiology & Ultrasound
Veterinary Radiology & Ultrasound 农林科学-兽医学
CiteScore
2.40
自引率
17.60%
发文量
133
审稿时长
8-16 weeks
期刊介绍: Veterinary Radiology & Ultrasound is a bimonthly, international, peer-reviewed, research journal devoted to the fields of veterinary diagnostic imaging and radiation oncology. Established in 1958, it is owned by the American College of Veterinary Radiology and is also the official journal for six affiliate veterinary organizations. Veterinary Radiology & Ultrasound is represented on the International Committee of Medical Journal Editors, World Association of Medical Editors, and Committee on Publication Ethics. The mission of Veterinary Radiology & Ultrasound is to serve as a leading resource for high quality articles that advance scientific knowledge and standards of clinical practice in the areas of veterinary diagnostic radiology, computed tomography, magnetic resonance imaging, ultrasonography, nuclear imaging, radiation oncology, and interventional radiology. Manuscript types include original investigations, imaging diagnosis reports, review articles, editorials and letters to the Editor. Acceptance criteria include originality, significance, quality, reader interest, composition and adherence to author guidelines.
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