Jin Young Park, Haesung Jun, Seung-Eun Lee, Ha-Kyeong Won, Sung-Yoon Kang, N. Kang, Ji-Yoon Oh, Young-Chan Kim, So-Young Park, Jin An, Y. Yoo, Mi-Yeong Kim, Hwa Young Lee, J.-S. Shim, Min-Hye Kim, Sae-Hoon Kim, Sang-Heon Kim, Yoon-Seok Chang, Sang-Hoon Kim, Byung Jae Lee, S. Birring, Woo-Jung Song
{"title":"Exploring the Concept of Disease Control in Chronic Cough","authors":"Jin Young Park, Haesung Jun, Seung-Eun Lee, Ha-Kyeong Won, Sung-Yoon Kang, N. Kang, Ji-Yoon Oh, Young-Chan Kim, So-Young Park, Jin An, Y. Yoo, Mi-Yeong Kim, Hwa Young Lee, J.-S. Shim, Min-Hye Kim, Sae-Hoon Kim, Sang-Heon Kim, Yoon-Seok Chang, Sang-Hoon Kim, Byung Jae Lee, S. Birring, Woo-Jung Song","doi":"10.1183/23120541.00320-2024","DOIUrl":null,"url":null,"abstract":"Disease control in chronic diseases is an overarching concept that reflects the degree to which the goals of therapy are met. However, to date, there is no consensus on the definition of disease control in chronic cough. This study aimed to provide a conceptual exploration of patient-reported cough control in chronic cough.This research is comprised of two sub-analyses. First, patients with chronic cough receiving care at referral clinics were evaluated. Correlation analyses were performed between patient-reported cough control (a 5-point Likert scale), cough-specific patient-reported outcomes (PROs), and generic health PRO scores. Second, a survey was conducted among patients with refractory chronic cough and physicians to identify factors pertinent to cough control.The analysis of 341 patients (mean age: 55.5±15.1 years; and female: 66.6%) revealed that cough control rating was moderately correlated with cough severity visual analogue scale and Leicester Cough Questionnaire scores, while demonstrating weaker correlations with cough-associated throat symptoms, cough-related complications, or general health-related quality of life (QoL). In the survey of patients and physicians, both groups considered certain factors, such as cough frequency, severity, and impact on QoL, to be relevant to the concept of cough control. However, patients rated “needs for cough rescue drug’ notably higher than physicians.Patient-reported cough control was associated with cough severity or impact on QoL, however, cough control may not be fully captured by conventional cough PRO measurement tools. Further studies are warranted to define the consensus and tools to measure disease control in chronic cough.","PeriodicalId":11739,"journal":{"name":"ERJ Open Research","volume":null,"pages":null},"PeriodicalIF":4.3000,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ERJ Open Research","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1183/23120541.00320-2024","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"RESPIRATORY SYSTEM","Score":null,"Total":0}
引用次数: 0
Abstract
Disease control in chronic diseases is an overarching concept that reflects the degree to which the goals of therapy are met. However, to date, there is no consensus on the definition of disease control in chronic cough. This study aimed to provide a conceptual exploration of patient-reported cough control in chronic cough.This research is comprised of two sub-analyses. First, patients with chronic cough receiving care at referral clinics were evaluated. Correlation analyses were performed between patient-reported cough control (a 5-point Likert scale), cough-specific patient-reported outcomes (PROs), and generic health PRO scores. Second, a survey was conducted among patients with refractory chronic cough and physicians to identify factors pertinent to cough control.The analysis of 341 patients (mean age: 55.5±15.1 years; and female: 66.6%) revealed that cough control rating was moderately correlated with cough severity visual analogue scale and Leicester Cough Questionnaire scores, while demonstrating weaker correlations with cough-associated throat symptoms, cough-related complications, or general health-related quality of life (QoL). In the survey of patients and physicians, both groups considered certain factors, such as cough frequency, severity, and impact on QoL, to be relevant to the concept of cough control. However, patients rated “needs for cough rescue drug’ notably higher than physicians.Patient-reported cough control was associated with cough severity or impact on QoL, however, cough control may not be fully captured by conventional cough PRO measurement tools. Further studies are warranted to define the consensus and tools to measure disease control in chronic cough.
慢性疾病的疾病控制是一个总体概念,反映了治疗目标的实现程度。然而,迄今为止,关于慢性咳嗽疾病控制的定义尚未达成共识。本研究旨在对慢性咳嗽患者报告的咳嗽控制情况进行概念性探讨。首先,对在转诊诊所接受治疗的慢性咳嗽患者进行评估。在患者报告的咳嗽控制情况(5 点李克特量表)、咳嗽特异性患者报告结果(PROs)和一般健康 PRO 评分之间进行了相关性分析。对 341 名患者(平均年龄:55.5±15.1 岁;女性:66.6%)的分析表明,咳嗽控制评分与咳嗽严重程度视觉模拟量表和莱斯特咳嗽问卷评分呈中度相关,而与咳嗽相关咽喉症状、咳嗽相关并发症或一般健康相关生活质量(QoL)的相关性较弱。在对患者和医生的调查中,双方都认为咳嗽频率、严重程度和对 QoL 的影响等因素与咳嗽控制的概念相关。患者报告的咳嗽控制情况与咳嗽严重程度或对 QoL 的影响有关,但传统的咳嗽 PRO 测量工具可能无法完全反映咳嗽控制情况。还需要进一步的研究来确定慢性咳嗽疾病控制的共识和测量工具。
期刊介绍:
ERJ Open Research is a fully open access original research journal, published online by the European Respiratory Society. The journal aims to publish high-quality work in all fields of respiratory science and medicine, covering basic science, clinical translational science and clinical medicine. The journal was created to help fulfil the ERS objective to disseminate scientific and educational material to its members and to the medical community, but also to provide researchers with an affordable open access specialty journal in which to publish their work.