{"title":"Generalities on a delayed spatiotemporal host-pathogen infection model with distinct dispersal rates","authors":"Djilali salih","doi":"10.1051/mmnp/2024008","DOIUrl":null,"url":null,"abstract":"We propose a general model to investigate the effect of the distinct dispersal coefficient {for the} infected and susceptible hosts on the pathogen dynamics. The mathematical challenge lies in the fact that the investigated model is partially degenerate and the solution map is not compact. The spatial heterogeneity of the model parameters and the distinct diffusion coefficients induce infection in the low-risk regions. In fact, as infection dispersal increases, the reproduction of the pathogen particles decreases. The dynamics of the investigated model is governed by the value of the basic reproduction number $R_0$. {If $R_0\\leq1$, then the} pathogen particles extinct, and for $R_0>1$ the pathogen particles persist, and we guarantees of the existence of at least one positive steady state. The asymptotic profile of the positive steady state is shown in the case when one or both diffusion coefficients for the host tends to zero or infinity.","PeriodicalId":2,"journal":{"name":"ACS Applied Bio Materials","volume":"59 13","pages":""},"PeriodicalIF":4.7000,"publicationDate":"2024-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"ACS Applied Bio Materials","FirstCategoryId":"100","ListUrlMain":"https://doi.org/10.1051/mmnp/2024008","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"MATERIALS SCIENCE, BIOMATERIALS","Score":null,"Total":0}
引用次数: 0
Abstract
We propose a general model to investigate the effect of the distinct dispersal coefficient {for the} infected and susceptible hosts on the pathogen dynamics. The mathematical challenge lies in the fact that the investigated model is partially degenerate and the solution map is not compact. The spatial heterogeneity of the model parameters and the distinct diffusion coefficients induce infection in the low-risk regions. In fact, as infection dispersal increases, the reproduction of the pathogen particles decreases. The dynamics of the investigated model is governed by the value of the basic reproduction number $R_0$. {If $R_0\leq1$, then the} pathogen particles extinct, and for $R_0>1$ the pathogen particles persist, and we guarantees of the existence of at least one positive steady state. The asymptotic profile of the positive steady state is shown in the case when one or both diffusion coefficients for the host tends to zero or infinity.
期刊介绍:
ACS Applied Bio Materials is an interdisciplinary journal publishing original research covering all aspects of biomaterials and biointerfaces including and beyond the traditional biosensing, biomedical and therapeutic applications.
The journal is devoted to reports of new and original experimental and theoretical research of an applied nature that integrates knowledge in the areas of materials, engineering, physics, bioscience, and chemistry into important bio applications. The journal is specifically interested in work that addresses the relationship between structure and function and assesses the stability and degradation of materials under relevant environmental and biological conditions.