Influencing Factors and Survival Analysis of Late Readmission after Percutaneous Coronary Intervention in Patients with Acute Myocardial Infarction

Lingjuan Zhou, Shoufang Pu, Jiaojiao Chen
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Abstract

Objective: This study aimed to explore the influencing factors analysis of late readmission after patients with acute myocardial infarction received percutaneous coronary intervention (PCI). Methods: A total of 368 patients with acute myocardial infarction who received PCI treatment in West China Hospital, Sichuan University/West China School of Nursing, Sichuan University from January 2018, to January 2021, were selected for the study. Among them, 110 subjects were excluded, and 258 subjects were finally included, of which 124 were readmitted and 134 were not readmitted. The baseline data and clinical characteristics of the patients were collected, and the influencing factors of readmission were analyzed by logistic regression analysis. The readmitted patients were followed up for 12 months. The Kaplan–Meier method was used to analyze the survival of patients with delayed readmitted and calculate the survival rate. Results: Significant differences were found between readmitted patients and non-readmitted patients in terms of age, chronic obstructive pulmonary disease (COPD), history of early coronary heart disease, history of hypertension, history of oral anticoagulant drugs, and left ventricle ejection fraction (LVEF, p < 0.05). No significant differences were observed in gender, body mass index, family history of acute myocardial infarction, history of chronic kidney disease, history of diabetes, history of smoking, history of drinking, and the number of implanted stents and diseased vessels (p > 0.05). Binary logistic regression analysis showed that age, COPD, history of premature coronary heart disease, history of oral anticoagulant drugs, and LVEF were important influencing factors of delayed readmission after PCI (all p < 0.05). Follow-up results showed that 125 patients survived and nine died among the delayed non-readmission patients after PCI. Among the patients with delayed readmission, 95 survived and 29 died. Kaplan–Meier survival analysis showed that the survival time of patients with delayed non-readmission was longer than that of patients with delayed readmission, and the difference was statistically significant (χ2 = 17.696, p < 0.001). Conclusion: Age, COPD, history of oral anticoagulant drugs, and LVEF are important influencing factors of delayed readmission after PCI, and the survival time of patients with delayed non-readmission is longer than that of patients with delayed readmission.
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急性心肌梗死患者经皮冠状动脉介入治疗后逾期再入院的影响因素和生存分析
研究目的本研究旨在探讨急性心肌梗死患者接受经皮冠状动脉介入治疗(PCI)后晚期再入院的影响因素分析。研究方法选取2018年1月至2021年1月在四川大学华西医院/四川大学华西护理学院接受PCI治疗的急性心肌梗死患者共368例作为研究对象。其中排除110例受试者,最终纳入258例受试者,其中再入院124例,未再入院134例。研究人员收集了患者的基线数据和临床特征,并通过逻辑回归分析法对再入院的影响因素进行了分析。对再次入院的患者进行了为期 12 个月的随访。采用 Kaplan-Meier 法分析延迟再入院患者的生存情况并计算生存率。结果显示在年龄、慢性阻塞性肺疾病(COPD)、早期冠心病病史、高血压病史、口服抗凝药物史和左心室射血分数(LVEF,P < 0.05)方面,再入院患者与非再入院患者存在显著差异。在性别、体重指数、急性心肌梗死家族史、慢性肾脏病史、糖尿病史、吸烟史、饮酒史、植入支架和病变血管数量等方面未发现明显差异(P > 0.05)。二元逻辑回归分析显示,年龄、慢性阻塞性肺病、早发冠心病史、口服抗凝药物史和 LVEF 是 PCI 后延迟再入院的重要影响因素(均 p <0.05)。随访结果显示,PCI术后延迟再入院患者中有125人存活,9人死亡。在延迟再入院的患者中,95 人存活,29 人死亡。卡普兰-梅耶生存分析显示,延迟未再入院患者的生存时间长于延迟再入院患者,差异有统计学意义(χ2 = 17.696,P < 0.001)。结论年龄、慢性阻塞性肺病、口服抗凝药物史和 LVEF 是 PCI 术后延迟再入院的重要影响因素,延迟未再入院患者的生存时间长于延迟再入院患者。
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