The serum leptin can be a predictable marker for gestational diabetes mellitus

Vemugadda Harika, Swathy Thilak, Radhakrishan Narayanswamy
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Abstract

This study assessed the serum leptin concentrations for development of gestational diabetes mellitusThis is a case-control study, included 120 participants (60: Gestational Diabetes Mellitus Cases and 60: Healthy Controls). We assed BMI, FBS, HbA1c, Lipid Profile and serum leptin. The serum leptin concentrations were significantly elevated in patients with gestational diabetes mellitus when compared to controls (P=0.001**). There was a significant positive correlation between the serum leptin and BMI, FBS, HbA1c, Total Cholesterol and LDL (P=0.001**). Based on study findings, significant elevated levels of serum leptin might be served as a marker for detection of gestational diabetes mellitus.
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血清瘦素可作为妊娠糖尿病的预测指标
这是一项病例对照研究,包括 120 名参与者(60 名妊娠糖尿病病例和 60 名健康对照者)。我们检测了体重指数(BMI)、脂肪肝指数(FBS)、糖化血红蛋白(HbA1c)、血脂谱和血清瘦素。与对照组相比,妊娠糖尿病患者的血清瘦素浓度明显升高(P=0.001**)。血清瘦素与 BMI、FBS、HbA1c、总胆固醇和低密度脂蛋白之间存在明显的正相关(P=0.001**)。根据研究结果,血清瘦素水平的明显升高可作为检测妊娠糖尿病的标志物。
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