Incidental pigmented basal cell carcinoma discovered on positron emission tomography (PET)

Yasaman Jazaeri, Véronique Del Marmol, Mariano Suppa, Nicolas Dumarey
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Abstract

Basal cell carcinoma (BCC), which frequently occurs in sun-exposed areas of the head and neck region, is the most common cutaneous malignancy but the least studied with radiologic imaging techniques. This article outlines the case of a 65-year-old male with a pigmented BCC of the right shoulder discovered on positron emission tomography-computed tomography (PET/CT). The lesion was initially suspected as a melanoma. However, the histopathological features showed a tumor of basaloid cells. PET/CT is an excellent technique for the detection of hypermetabolic tumors, such as melanoma, squamous cell and Merkel cell carcinomas, in lymph nodes and distant organs. The usefulness of PET is limited for slowly growing tumors, such as BCC. However, PET/CT can be useful for the detection of distant metastasis in locally advanced BCC as well as in the follow-up of locally advanced BCC on Hedgehog inhibitors.

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正电子发射断层扫描(PET)发现的偶发色素性基底细胞癌
基底细胞癌(BCC)经常发生在头颈部暴露于阳光的部位,是最常见的皮肤恶性肿瘤,但放射成像技术对其研究最少。本文概述了一名 65 岁男性的病例,他在正电子发射断层扫描-计算机断层扫描(PET/CT)中发现右肩有色素性 BCC。病变最初被怀疑为黑色素瘤。然而,组织病理学特征显示这是一个类基底细胞肿瘤。PET/CT 是检测淋巴结和远处器官高代谢肿瘤(如黑色素瘤、鳞状细胞癌和梅克尔细胞癌)的绝佳技术。PET 对生长缓慢的肿瘤(如 BCC)的作用有限。不过,PET/CT 可用于检测局部晚期 BCC 的远处转移,以及对使用刺猬抑制剂的局部晚期 BCC 进行随访。
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