A Case of Refractory Cutaneous Sarcoidosis Successfully Treated with Infliximab

Roudha Al-Dehneem
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Abstract

Sarcoidosis is an inflammatory granulomatous disease affecting multiple organs with cutaneous sarcoidosis occurring in 25% of patients. There are several treatment options available, but alternative therapies should be considered in patients with refractory disease to standard intervention. Though they are not been FDA-approved for sarcoidosis, TNF-a inhibitors have demonstrated significant therapeutic intervention targeting proinflammatory cytokines involves in pathogenesis of sarcoidosis.  Herein, we present a case of refractory cutaneous sarcoidosis successfully treated with infliximab therapy with significant hair regrowth on the scalp.
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一例使用英夫利西单抗成功治疗的难治性皮肤肉样瘤病例
肉样瘤病是一种影响多个器官的炎性肉芽肿疾病,25% 的患者会患上皮肤肉样瘤病。目前有多种治疗方法可供选择,但对于标准干预治疗无效的患者,应考虑使用替代疗法。TNF-a抑制剂虽然尚未获得美国食品及药物管理局(FDA)批准用于肉样瘤病的治疗,但其针对参与肉样瘤病发病机制的促炎细胞因子的治疗干预效果显著。 在此,我们介绍了一例使用英夫利昔单抗治疗成功的难治性皮肤肉样瘤病病例,患者头皮上的毛发明显再生。
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