THE RELATIONSHIP BETWEEN OXIDATIVE STRESS AND NEUROLOGICAL DISORDERS: MINI REVIEW

Z.D. Kulbayeva, D.A. Klyuyev, S.K. Sh, A.A. Muratbek
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Abstract

Oxidative stress is one of the main causes of neuronal dysfunction and death, mainly due to excessive formation of reactive oxygen species and depletion of antioxidant reserves. Oxidative stress is characterized by an imbalance between the production of reactive oxygen species (ROS) and antioxidant defense mechanisms of the body. This process is involved in the onset and development of many neurological diseases. In this review, we analyzed and summarized the results of studies showing the association of neurological diseases, such as stroke, Parkinson’s disease, and other neurological diseases, with excessive formation of oxidative stress products. This article aims to provide an overview of the relationship between oxidative stress and a range of neurological conditions, shedding light on the underlying mechanisms and potential therapeutic implications.
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氧化应激与神经系统疾病的关系:微型综述
氧化应激是导致神经元功能障碍和死亡的主要原因之一,其主要原因是活性氧的过度形成和抗氧化剂储备的耗竭。氧化应激的特点是活性氧(ROS)的产生与机体抗氧化防御机制之间的不平衡。这一过程与许多神经系统疾病的发生和发展有关。在这篇综述中,我们分析并总结了显示神经系统疾病(如中风、帕金森病和其他神经系统疾病)与氧化应激产物过度形成有关的研究结果。本文旨在概述氧化应激与一系列神经系统疾病之间的关系,揭示其潜在机制和治疗意义。
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