Prevalence of multidrug resistance pathogens in dermatology: A retrospective study in Romania, 2018-2022

Abstract

Antimicrobial resistance (AMR) is now a major challenge to clinicians in treating patients. The purpose of our study was to determine the incidence of multidrug resistant (MDR) strains and antibiotic resistance profile in department of dermatology-venereology from a Romanian infectious disease’s hospital. We analyzed 1,152 bacterial strains, we obtained 34.5% MDR strains, identifying the following species: staphylococcus aureus 43.6%, enterococcus spp 16.7%, escherichia coli 31.0%, proteus spp 27.1%, klebsiella spp. 22.4%, pseudomonas spp. 34.8%. Overall, the rate of methicillin-resistant staphylococcus aureus was 76.1%; extended spectrum beta-lactamase production was 46.1% for escherichia coli and 66.0% for klebsiella pneumoniae; carbapenems-resistance was 51.0% for pseudomonas aeruginosa. All strains of E. coli and klebsiella were sensitive to meropenem. Our results confirm the high level of AMR, and continuous monitoring is essential for updating the local diagnostic and treatment protocols for dermatological infections.