Long-term benzodiazepine prescriptions in community psychiatry clinics

IF 17.7 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-05-03 DOI:10.4102/sajpsychiatry.v30i0.2181
Machipi A. Tau, Mohamed Y.H. Moosa, Fatima Y. Jeenah
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Abstract

Background: Anecdotal evidence indicates that the prevalence of long-term benzodiazepine prescription is high and not in accordance with accepted prescribing guidelines.Aim: To determine the prevalence of long-term prescriptions of benzodiazepines and associations thereof in community psychiatry clinics.Setting: Of the 27 community psychiatry clinics, 5 were randomly selected.Methods: A descriptive, retrospective, and cross-sectional record review of files of 126 adult patients was conducted, to obtain sociodemographic and clinical characteristics. Descriptive statistics were presented as proportions and percentages. Fisher’s exact test was used to determine any associations between long-term benzodiazepines use and demographic and clinical variables. Regression analyses were performed to determine the significance of any such associations.Results: Approximately one out of every four patients were prescribed benzodiazepines. Most of the patients were males aged between 18 and 50 years, single and unemployed. The most common psychiatric diagnoses were bipolar disorders and psychotic disorders, and the majority had no comorbid medical illnesses or substance use. Ninety-three per cent of the patients were prescribed long-term (more than 180 days) benzodiazepines. There were no statistically significant associations between prescribing patterns and any sociodemographic and clinical characteristics (p  0.05).Conclusion: This study found that nearly all the benzodiazepine prescriptions were long-term (over 180 days) and no statistically significant associations between this practice and any sociodemographic and clinical characteristics could be established.Contribution: There is high prevalence rate of long-term benzodiazepine prescription in community psychiatry clinics, and as such clinical monitoring systems need to be established and enforced.
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社区精神病诊所的长期苯并二氮杂卓处方
背景:轶事证据表明,苯二氮卓类药物的长期处方率很高,而且不符合公认的处方指南:轶事证据表明,苯二氮卓类药物的长期处方率很高,而且不符合公认的处方指南。目的:确定社区精神病诊所苯二氮卓类药物长期处方的普遍性及其关联:在 27 家社区精神病诊所中随机抽取 5 家:方法:对 126 名成年患者的档案进行描述性、回顾性和横断面记录审查,以获得社会人口学和临床特征。描述性统计以比例和百分比表示。使用费雪精确检验来确定长期使用苯二氮卓类药物与人口统计学和临床变量之间是否存在关联。此外,还进行了回归分析,以确定任何此类关联的显著性:大约每四名患者中就有一人服用苯二氮卓类药物。大多数患者为男性,年龄在 18 岁至 50 岁之间,单身,无业。最常见的精神病诊断是躁郁症和精神病性障碍,大多数患者没有合并内科疾病或使用药物。93%的患者长期(180 天以上)服用苯二氮卓类药物。处方模式与任何社会人口学和临床特征之间均无统计学意义(P 0.05):本研究发现,几乎所有苯二氮卓类药物的处方都是长期处方(超过 180 天),这种做法与任何社会人口学和临床特征之间都没有统计学意义上的关联:贡献:在社区精神病学诊所中,长期开苯二氮卓类药物处方的发生率很高,因此需要建立并实施临床监测系统。
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来源期刊
Accounts of Chemical Research
Accounts of Chemical Research 化学-化学综合
CiteScore
31.40
自引率
1.10%
发文量
312
审稿时长
2 months
期刊介绍: Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
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