THE EFFECTIVENESS OF AUTOFLUORESCENCE STOMATOSCOPY AS THE MAIN METHOD OF EARLY DIAGNOSIS OF PRECANCEROUS DISEASES OF THE ORAL MUCOSA

Vyacheslav Popov, Aleksey Karyakin, Olga Karyakina, Aleksandra Dubinina
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Abstract

Importance Currently, the prevalence of various diseases of the oral mucosa in the world has increased significantly (from 15.2% to 49.1%). Oncological pathology should be attributed to a separate group of diseases. In order to actively identify precancerous processes of the oral cavity, along with traditional methods of examination of the maxillofacial region, oncoscreening of the mucous membrane and organs of the oral cavity is mandatory. One of the possible methods of oncoscreening is autofluorescence stomatoscopy. Objectives To clarify the effectiveness of autofluorescence stomatoscopy as the main method of early diagnosis of precancerous diseases of the oral mucosa, its advantages and disadvantages. Methods In the process of investigating the effectiveness of autofluorescence stomatoscopy, methods of qualitative analysis and synthesis of available scientific literature on autofluorescence stomatoscopy were used. Conclusions It is concluded that the use of autofluorescence stomatoscopy for the early diagnosis of precancerous diseases of the oral mucosa remains controversial. Some clinicians believe that the introduction of autofluorescence stomatoscopy into the practice of a dentist as an additional method of oncoscreening of the oral mucosa is not only relevant, but also necessary; and the analysis of the light glow corresponds to the results of a biopsy. However, other researchers have concluded that the AFS-method will not replace the gold standard of histological examination, due to the low specificity of the method, the study can lead to overdiagnosis, and it can only be used by experienced clinicians to find the boundaries of precancerous lesions of the oral cavity for taking a biopsy in an altered mucous membrane.
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自发荧光口腔镜检查作为早期诊断口腔粘膜癌前疾病主要方法的有效性
重要性 目前,世界上各种口腔黏膜疾病的发病率大幅上升(从 15.2% 上升到 49.1%)。肿瘤病理学应归为一类独立的疾病。为了积极发现口腔癌前病变,除了传统的颌面部检查方法外,还必须对口腔黏膜和器官进行筛查。自动荧光口腔镜检查是其中一种可行的检查方法。目的 明确自动荧光口腔镜作为早期诊断口腔黏膜癌前疾病的主要方法的有效性及其优缺点。方法 在研究自动荧光口腔镜检查有效性的过程中,采用了定性分析和综合现有关于自动荧光口腔镜检查的科学文献的方法。结论 使用自动荧光口腔镜进行口腔黏膜癌前疾病的早期诊断仍存在争议。一些临床医生认为,将自动荧光口腔镜检查作为口腔黏膜筛查的附加方法引入牙科医生的工作中不仅有意义,而且很有必要;对光辉的分析与活组织检查的结果相对应。然而,其他研究人员认为,AFS 方法不会取代组织学检查的金标准,因为该方法的特异性较低,研究可能导致过度诊断,只有经验丰富的临床医生才能使用该方法找到口腔癌前病变的边界,以便在改变的粘膜中进行活检。
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