Comprehensive CT Imaging Analysis of Primary Colorectal Squamous Cell Carcinoma: A Retrospective Study

IF 2.2 4区医学 Q2 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Tomography Pub Date : 2024-05-01 DOI:10.3390/tomography10050052

Eun Ju Yoon, Sang Gook Song, Jin Woong Kim, Hyun Chul Kim, Hyung-Joong Kim, Young Hoe Hur, Jun Hyung Hong

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Abstract

The aim of this study was to evaluate the findings of CT scans in patients with pathologically confirmed primary colorectal squamous-cell carcinoma (SCC). The clinical presentation and CT findings in eight patients with pathologically confirmed primary colorectal squamous-cell carcinoma were retrospectively reviewed by two gastrointestinal radiologists. Hematochezia was the most common symptom (n = 5). The tumors were located in the rectum (n = 7) and sigmoid colon (n = 1). The tumors showed circumferential wall thickening (n = 4), bulky mass (n = 3), or eccentric wall thickening (n = 1). The mean maximal wall thickness of the involved segment was 29.1 mm ± 13.4 mm. The degree of tumoral enhancement observed via CT was well enhanced (n = 4) or moderately enhanced (n = 4). Necrosis within the tumor was found in five patients. The mean total number of metastatic lymph nodes was 3.1 ± 3.3, and the mean short diameter of the largest metastatic lymph node was 16.6 ± 5.7 mm. Necrosis within the metastatic node was observed in six patients. Invasions to adjacent organs were identified in five patients (62.5%). Distant metastasis was detected in only one patient. In summary, primary SCCs that arise from the colorectum commonly present as marked invasive wall thickening or a bulky mass with heterogeneous well-defined enhancement, internal necrosis, and large metastatic lymphadenopathies.

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原发性大肠鳞状细胞癌的全面 CT 成像分析：一项回顾性研究

本研究旨在评估病理确诊的原发性结直肠鳞状细胞癌（SCC）患者的 CT 扫描结果。两名胃肠道放射科医生对 8 名病理确诊的原发性结直肠鳞状细胞癌患者的临床表现和 CT 结果进行了回顾性研究。出血是最常见的症状（5 例）。肿瘤位于直肠（7 例）和乙状结肠（1 例）。肿瘤表现为周壁增厚（4 例）、肿块（3 例）或偏心壁增厚（1 例）。受累区段的平均最大壁厚为 29.1 mm ± 13.4 mm。CT 观察到的肿瘤强化程度为良好强化（4 例）或中度强化（4 例）。5名患者的肿瘤内部出现坏死。转移淋巴结的平均总数为（3.1 ± 3.3）个，最大转移淋巴结的平均短直径为（16.6 ± 5.7）毫米。六名患者的转移淋巴结出现坏死。五名患者（62.5%）发现邻近器官受到侵犯。只有一名患者发现了远处转移。总之，来自结直肠的原发性 SCC 通常表现为明显的侵袭性壁增厚或肿块，伴有异质性界限清晰的强化、内部坏死和大的转移淋巴结。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Tomography Medicine-Radiology, Nuclear Medicine and Imaging

CiteScore

2.70

自引率

10.50%

发文量

222

期刊介绍： TomographyTM publishes basic (technical and pre-clinical) and clinical scientific articles which involve the advancement of imaging technologies. Tomography encompasses studies that use single or multiple imaging modalities including for example CT, US, PET, SPECT, MR and hyperpolarization technologies, as well as optical modalities (i.e. bioluminescence, photoacoustic, endomicroscopy, fiber optic imaging and optical computed tomography) in basic sciences, engineering, preclinical and clinical medicine. Tomography also welcomes studies involving exploration and refinement of contrast mechanisms and image-derived metrics within and across modalities toward the development of novel imaging probes for image-based feedback and intervention. The use of imaging in biology and medicine provides unparalleled opportunities to noninvasively interrogate tissues to obtain real-time dynamic and quantitative information required for diagnosis and response to interventions and to follow evolving pathological conditions. As multi-modal studies and the complexities of imaging technologies themselves are ever increasing to provide advanced information to scientists and clinicians. Tomography provides a unique publication venue allowing investigators the opportunity to more precisely communicate integrated findings related to the diverse and heterogeneous features associated with underlying anatomical, physiological, functional, metabolic and molecular genetic activities of normal and diseased tissue. Thus Tomography publishes peer-reviewed articles which involve the broad use of imaging of any tissue and disease type including both preclinical and clinical investigations. In addition, hardware/software along with chemical and molecular probe advances are welcome as they are deemed to significantly contribute towards the long-term goal of improving the overall impact of imaging on scientific and clinical discovery.