A Retrospective Comparative Chart Review of Hearing Recovery in Neural and Sensory Type Sudden Sensorineural Hearing Loss Patients.

IF 1.1 4区 医学 Q3 OTORHINOLARYNGOLOGY Journal of Laryngology and Otology Pub Date : 2024-11-01 Epub Date: 2024-05-20 DOI:10.1017/S0022215124000781
Rebecca Z Xu, Ru C Guo, Printha Wijesinghe, Temitope G Joshua, Aysha Ayub, Melissa Lee, Desmond A Nunez
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Abstract

Objective: While the pathogenesis of sudden sensorineural hearing loss is thought to be localised to the cochlea, recent microRNA findings suggest a neuro-topic localisation in some patients. This study distinguishes if neural and non-neural groups differ in hearing recovery.

Methods: Neural-type hearing loss was defined as a presenting word recognition score less than 60 per cent, with a word recognition score reduction greater than 20 per cent than expected based on the averaged pure tone audiometry. Hearing recovery was defined as an improvement of greater than or equal to 10 decibels in pure tone audiometric thresholds.

Results: Eight of 12 and 24 of 36 of neural and non-neural hearing loss patients demonstrated hearing recovery, respectively. The affected ear's word recognition score (per cent) change with treatment were different between the neural and non-neural groups (46.9 ± 29.8 vs 3.2 ± 25.8 (p < 0.0001)).

Conclusion: The hearing recovery rate in neural and non-neural hearing loss groups was similar. Patients with neural-type hearing loss demonstrated greater word recognition score recovery post treatment than those in the sensory group.

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神经型和感觉型突发性感音神经性听力损失患者听力恢复情况的回顾性病历对比。
目的:虽然突发性感音神经性听力损失的发病机制被认为是耳蜗定位,但最近的microRNA研究结果表明,在一些患者中存在神经位点定位。本研究将区分神经组和非神经组在听力恢复方面是否存在差异:方法:神经型听力损失的定义是:出现的单词识别率低于 60%,根据平均纯音测听结果,单词识别率比预期降低 20%。听力恢复的定义是纯音测听阈值提高大于或等于 10 分贝:结果:神经性和非神经性听力损失患者分别有 12 人和 36 人中的 8 人和 24 人实现了听力恢复。神经组和非神经组患耳的单词识别得分(百分比)随治疗的变化不同(46.9 ± 29.8 vs 3.2 ± 25.8 (p < 0.0001)):结论:神经性和非神经性听力损失组的听力恢复率相似。结论:神经性听力损失组和非神经性听力损失组的听力恢复率相似,神经性听力损失患者在治疗后的单词识别得分恢复率高于感官性听力损失组。
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来源期刊
Journal of Laryngology and Otology
Journal of Laryngology and Otology 医学-耳鼻喉科学
CiteScore
3.20
自引率
11.80%
发文量
593
审稿时长
3-6 weeks
期刊介绍: The Journal of Laryngology & Otology (JLO) is a leading, monthly journal containing original scientific articles and clinical records in otology, rhinology, laryngology and related specialties. Founded in 1887, JLO is absorbing reading for ENT specialists and trainees. The journal has an international outlook with contributions from around the world, relevant to all specialists in this area regardless of the country in which they practise. JLO contains main articles (original, review and historical), case reports and short reports as well as radiology, pathology or oncology in focus, a selection of abstracts, book reviews, letters to the editor, general notes and calendar, operative surgery techniques, and occasional supplements. It is fully illustrated and has become a definitive reference source in this fast-moving subject area. Published monthly an annual subscription is excellent value for money. Included in the subscription is access to the JLO interactive web site with searchable abstract database of the journal archive back to 1887.
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