Related barriers to using HIV pre-exposure prophylaxis among MSM: A multicentre cross-sectional survey

IF 2.8 3区医学 Q2 INFECTIOUS DISEASES HIV Medicine Pub Date : 2024-05-21 DOI:10.1111/hiv.13663

Xue Yang, Guang Zhang, Wenting Kang, Jiahuan Guo, An Liu, Houlin Tang, Tongtong Liu, Lijun Sun

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Abstract

Objective

The objective of this study was to gain insight into the barriers hindering the use of pre-exposure prophylaxis (PrEP) among men who have sex with men (MSM) in five cities in China.

Methods

MSM were recruited via community-based organizations in an online “snowball” manner. Participants completed the questionnaire anonymously and shared it with key MSM peers (seeds) in five cities in China. Based on the results of univariate analysis, we used a structural equation model to analyse the role of PrEP knowledge awareness, PrEP counselling, and other behavioural variables on PrEP use.

Results

The study collected a total of 4223 valid questionnaires, and 18.2% of participants reported PrEP use. The results of the standardized total effects showed that the following paths were statistically significant (p < 0.05): from the age of first sex with men to PrEP knowledge awareness (β = −0.113) and PrEP use (β = 0.042); from high-risk sexual behaviour scores to PrEP counselling (β = 0.039) and PrEP use (β = 0.103); from the number of HIV tests in the last year to PrEP knowledge awareness (β = 0.034), PrEP counselling (β = 0.170), and PrEP use (β = 0.197); from the level of self-perceived risk of HIV infection to PrEP counselling (β = −0.115); from PrEP knowledge awareness to PrEP use (β = −0.049); and from PrEP counselling to PrEP use (β = 0.420).

Conclusions

The proportion of PrEP use among MSM was relatively low. Age at first sex with men, number of HIV tests, high-risk sexual behaviour, and PrEP counselling had a positive effect on PrEP use, whereas PrEP knowledge awareness had an inverse effect on PrEP use.

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男男性行为者使用艾滋病暴露前预防措施的相关障碍：多中心横断面调查。

研究目的本研究旨在深入了解在中国五个城市的男男性行为者（MSM）中使用暴露前预防疗法（PrEP）的障碍：方法：通过社区组织以 "滚雪球 "的方式在线招募男男性行为者。参与者匿名填写问卷，并与中国五个城市的主要 MSM 同伴（种子选手）分享问卷。在单变量分析结果的基础上，我们使用结构方程模型分析了PrEP知识认知、PrEP咨询和其他行为变量对PrEP使用的作用：研究共收集了 4223 份有效问卷，18.2% 的参与者报告使用了 PrEP。标准化总效应的结果显示，以下路径具有统计学意义（p 结论：PrEP 在男男性行为者中的使用比例与 PrEP 在男男性行为者中的使用比例之间存在显著差异：男男性行为者中使用 PrEP 的比例相对较低。首次与男性发生性关系的年龄、HIV 检测次数、高危性行为和 PrEP 咨询对 PrEP 的使用有正向影响，而 PrEP 知识认知对 PrEP 的使用有反向影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

HIV Medicine 医学-传染病学

CiteScore

5.10

自引率

10.00%

发文量

167

审稿时长

6-12 weeks

期刊介绍： HIV Medicine aims to provide an alternative outlet for publication of international research papers in the field of HIV Medicine, embracing clinical, pharmocological, epidemiological, ethical, preclinical and in vitro studies. In addition, the journal will commission reviews and other feature articles. It will focus on evidence-based medicine as the mainstay of successful management of HIV and AIDS. The journal is specifically aimed at researchers and clinicians with responsibility for treating HIV seropositive patients.